{ "generatedAt": "2026-06-17T16:11:36.131Z", "query": "artificial intelligence OR large language model OR retrieval augmented generation OR robotics OR medicine", "count": 112, "papers": [ { "id": "OpenAlex-667574757265206f662061692069", "title": "Future of AI in English Language Education: Trends and Predictions", "authors": "Prof. Jagadeesh Nerlekar, K Munianjinappa", "source": "OpenAlex", "field": "Artificial Intelligence", "date": "2026-12-01", "abstract": "Abstract Artificial intelligence (AI) is transforming English language education (ELE) by enabling personalized learning, automated assessment, adaptive content generation, and immersive practice environments. This paper synthesizes current developments, identifies emergent trends, and offers evidence-informed predictions about how AI will shape classroom practice, curriculum design, assessment, teacher roles, and policy over the next decade. Drawing on interdisciplinary literature from computer-assisted language learning (CALL), intelligent tutoring systems (ITS), natural language processing (NLP), and educational policy, the paper argues that the most significant near-term impact will stem from hybrid systems that combine large language models (LLMs) with pedagogically informed scaffolding and teacher mediation. Key trends discussed include (1) ubiquitous personalized feedback and adaptive pathways; (2) automated, formative assessment with rich analytics; (3) realistic speaking/listening practice via multimodal conversational agents and immersive virtual environments; (4) AI-assisted material creation and differentiation for diverse learner needs; and (5) data-driven teacher support and professional development. Predictions address likely improvements in scalability and access, as well as persistent challenges: bias and fairness in language models, privacy and data governance, over-reliance on automated feedback, and the need for robust teacher training and curricular alignment. The paper concludes with practical recommendations for educators, institutions, and policymakers to harness AI’s affordances while safeguarding equity, transparency, and pedagogical quality. These include adopting hybrid human–AI workflows, emphasizing explainability and interpretability in tools, developing clear data-ethics policies, investing in teacher capacity building, and prioritizing research-practice partnerships. The analysis aims to be actionable for practitioners and decision-makers planning for an AI-augmented future of English language learning. Keywords: artificial intelligence, English language education, adaptive learning, large language models, assessment, teacher role, ethics", "url": "https://doi.org/10.5281/zenodo.18739462", "doi": "https://doi.org/10.5281/zenodo.18739462", "keywords": [ "LLM", "agent", "multimodal" ], "citations": [], "sourceId": "https://openalex.org/W7131071032", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-667574757265206f662061692069", "title": "Future of AI in English Language Education: Trends and Predictions", "authors": "Prof. Jagadeesh Nerlekar, K Munianjinappa", "source": "OpenAlex", "field": "Artificial Intelligence", "date": "2026-12-01", "abstract": "Abstract Artificial intelligence (AI) is transforming English language education (ELE) by enabling personalized learning, automated assessment, adaptive content generation, and immersive practice environments. This paper synthesizes current developments, identifies emergent trends, and offers evidence-informed predictions about how AI will shape classroom practice, curriculum design, assessment, teacher roles, and policy over the next decade. Drawing on interdisciplinary literature from computer-assisted language learning (CALL), intelligent tutoring systems (ITS), natural language processing (NLP), and educational policy, the paper argues that the most significant near-term impact will stem from hybrid systems that combine large language models (LLMs) with pedagogically informed scaffolding and teacher mediation. Key trends discussed include (1) ubiquitous personalized feedback and adaptive pathways; (2) automated, formative assessment with rich analytics; (3) realistic speaking/listening practice via multimodal conversational agents and immersive virtual environments; (4) AI-assisted material creation and differentiation for diverse learner needs; and (5) data-driven teacher support and professional development. Predictions address likely improvements in scalability and access, as well as persistent challenges: bias and fairness in language models, privacy and data governance, over-reliance on automated feedback, and the need for robust teacher training and curricular alignment. The paper concludes with practical recommendations for educators, institutions, and policymakers to harness AI’s affordances while safeguarding equity, transparency, and pedagogical quality. These include adopting hybrid human–AI workflows, emphasizing explainability and interpretability in tools, developing clear data-ethics policies, investing in teacher capacity building, and prioritizing research-practice partnerships. The analysis aims to be actionable for practitioners and decision-makers planning for an AI-augmented future of English language learning. Keywords: artificial intelligence, English language education, adaptive learning, large language models, assessment, teacher role, ethics", "url": "https://doi.org/10.5281/zenodo.18739461", "doi": "https://doi.org/10.5281/zenodo.18739461", "keywords": [ "LLM", "agent", "multimodal" ], "citations": [], "sourceId": "https://openalex.org/W7131132383", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-646562756767696e672064656275", "title": "Debugging debugging information using dynamic call trees", "authors": "J. Ryan Stinnett, Stephen Kell", "source": "OpenAlex", "field": "Interdisciplinary", "date": "2026-10-05", "abstract": "Debugging tools rely on compiler-generated metadata to present a source-language view, but current compilers often throw away or corrupt debugging information in optimised programs.Attempts to test debugging information are confounded by ad-hoc limitations of the debug info formats and a lack of clarity on whether the compiler or the format is to blame for any given loss.Adopting the \"residual program\" conceptual view of debug info, we conduct a study of the quality of debugging information in respect of the source-level dynamic call trees it can recover.We compare the trees recovered from optimised and unoptimised versions of the same program, producing a classification of the observed divergences.For each class, we analyse whether format or compiler is to blame and identify specific ways to address these defects.We also validate our classification across a larger collection of well-known codebases.", "url": "https://kclpure.kcl.ac.uk/portal/en/publications/f82a4449-b7f2-4977-88a4-94dc35b8459c", "doi": "", "keywords": [], "citations": [], "sourceId": "https://openalex.org/W7128571704", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-6c657665726167696e6720637279", "title": "Leveraging Cryptographic Simulator Synthesis for Formally Verifying the FOO E-Voting Protocol", "authors": "David Baelde, Adrien Koutsos, Justine Sauvage", "source": "OpenAlex", "field": "Artificial Intelligence", "date": "2026-08-12", "abstract": "International audience", "url": "https://inria.hal.science/hal-05453231", "doi": "", "keywords": [ "RAG" ], "citations": [], "sourceId": "https://openalex.org/W7124231798", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-746865206669727374207265666c", "title": "The First Reflection in Creative Experience (RiCE) Workshop", "authors": "Corey Ford, Olga Sutskova, Samuel Rhys Cox, Sarah Sterman, Max Kreminski, Rosa van Koningsbruggen, Anqi Wang, Ege Otenen, Karly Ross, Giulia Di Fede, Yinmiao Li, Salvatore Andolina, Marit Bentvelzen, Pan Hui, Nick Bryan-Kinns", "source": "OpenAlex", "field": "Artificial Intelligence", "date": "2026-07-13", "abstract": "Reflection and metacognition are central to the creative user experience. However, most HCI research on reflection focuses on clear, task-oriented goals such as to reflect on personal data or pedagogical outcomes. This contrasts with the open-ended and challenging to articulate goals of creative user experiences. For the first time, this workshop brings together interdisciplinary researchers, designers, educators, and artists across HCI, Cognitive Science, Design, AI, Learning Sciences, and Digital Art to examine reflection in creative interaction. The workshop will discuss themes, drawn from earlier discussions with HCI researchers and artists, on: how best to capture reflection in creative contexts, how to leverage the arts to support reflection for ethical change, and how to design creative AI that enhances – not hinders – critical thinking. By bringing interdisciplinary perspectives on reflection into discussion, the workshop will develop a guiding taxonomy for reflection in creative interaction to inform future creative practice and tool development.", "url": "https://ualresearchonline.arts.ac.uk/view/creators/Ford=3ACorey=3A=3A.html>", "doi": "", "keywords": [ "RAG" ], "citations": [], "sourceId": "https://openalex.org/W7153411310", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-6e65676f74696174696e67206574", "title": "Negotiating Ethical Coexistence with AI: A Grounded Theory of Japanese Students’ Conditional Trust, Agency, and the Development of Critical AI Literacy", "authors": "Eylem Taş, Eva Bittner", "source": "OpenAlex", "field": "Interdisciplinary", "date": "2026-07-05", "abstract": "Generative Artificial Intelligence (GenAI) is increasingly reshaping how students learn, reason, and create, raising pressing questions about agency, trust, and moral responsibility. While information systems (IS) research has emphasized organizational governance and design ethics, less is known about how students develop ethical awareness in everyday AI use. This study applies a systematic grounded theory lens to a mixed-format survey of 69 Japanese university students. We develop a process model of how students negotiate ethical coexistence with GenAI. The analysis identifies an iterative moral trajectory, from recognition of power and risk to ethical anxiety, reflexive evaluation, and conditional trust. We capture this process in the grounded model Negotiating Ethical Coexistence with AI (NECoAI). NECoAI conceptualizes ethical learning as an ongoing process of moral calibration rather than a static belief or competence. The findings extend responsible AI research in IS by centering ethical sensemaking in use and emphasizing reflective, human-centered AI education.", "url": "https://aisel.aisnet.org/pacis2026/is_education/is_education/15", "doi": "", "keywords": [], "citations": [], "sourceId": "https://openalex.org/W7164724314", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-6d697469676174696e6720617474", "title": "Mitigating Attention Bias in Index-Fund Investment: AI-Enabled Decision Support for Retail Investors", "authors": "Ruiyi Ma, Ying Zhang, David Sundaram", "source": "OpenAlex", "field": "Interdisciplinary", "date": "2026-07-05", "abstract": "In information-intensive and high-noise stock markets, investors often face information overload and rely on heuristics and selective attention, which can lead to cognitive biases and reduced decision quality. AI can process vast datasets, identify non-linear patterns, and provide real-time decision support, offering opportunities to improve investment decision-making. Through a progressive systematic literature review, this study finds that incorporating cognitive-bias mechanisms as design drivers in AI-enabled investment artifacts has not been studied, and research on AI-enabled decision support in the index-fund context remains limited. The review identifies attention bias as a focal mechanism, particularly salient for retail investors. Based on these findings, this study develops a conceptual AI-enabled decision support artifact for index fund investment to mitigate retail investors’ attention bias and improve decision quality. A system dynamics simulation provides preliminary directional validation, and an evaluation agenda is outlined for future artifact development and evaluation.", "url": "https://aisel.aisnet.org/pacis2026/blockfintech/blockfintech/1", "doi": "", "keywords": [], "citations": [], "sourceId": "https://openalex.org/W7164715552", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-7768656e206d6f64656c73206d65", "title": "When Models Meet Sensors – A Structured Review and IS Research Agenda for Generative AI-Enabled IoT Artifacts", "authors": "Arnold F. Arz von Straussenburg, Dennis M. Riehle", "source": "OpenAlex", "field": "Artificial Intelligence", "date": "2026-07-05", "abstract": "The Internet of Things generates vast streams of temporal data, yet translating these streams into actionable knowledge remains a persistent design challenge for Information Systems research. Generative AI, particularly Large Language Models, introduces new possibilities for interpreting, mediating, and augmenting such data. However, the emerging literature at this intersection is fragmented across technical domains and lacks systematic consolidation from a sociotechnical design perspective. This paper presents a structured review of 35 recent studies combining Generative AI with IoT and adjacent time series contexts. A two-stage analytical strategy pairs AI-assisted topic modeling with interpretive concept coding to identify four recurring themes: temporal intelligence through hybrid architectures, agentic mediation between users and sensor infrastructures, explainability demands in anomaly detection, and generative augmentation beyond forecasting. The synthesis reveals strong model-centric experimentation alongside underdeveloped organizational, individual, and societal design dimensions. These imbalances are consolidated into a research agenda for future artifact-oriented IS inquiry.", "url": "https://aisel.aisnet.org/pacis2026/iot_smartcity/iot_smartcity/11", "doi": "", "keywords": [ "RAG", "agent" ], "citations": [], "sourceId": "https://openalex.org/W7164719164", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-746563686e6f6c6f677920696e74", "title": "Technology Integration and Responder Workflow in a South African Emergency Contact Centre: An Activity Theory Case Study", "authors": "Keaton Cupido Solomons, Irwin Brown", "source": "OpenAlex", "field": "Biomedicine", "date": "2026-07-05", "abstract": "Emergency Contact Centres (ECCs) rely on integrated technologies to improve response, yet these tools can disrupt workflows. This study investigates how integrations shape human activity in a South African ECC managing emergency hotlines. Guided by Activity Theory (AT) and an interpretivist case study design, semi-structured interviews were conducted with 12 participants. Three system-level contradictions were identified: the priority of speed over comprehensive data capture (C1), interoperability failure and workarounds (C2), and organisational and technical inertia (C3). This research contributes a human-centric account of technology adoption, showing how external Key Performance Indicators (KPIs) override tool design, forcing responders to navigate systemic friction. Practical implications include aligning KPIs with clinical data entry, enhancing Application Programming Interface (API) interoperability, and supporting employees to overcome resistance. This study provides insights into adopting complex Information Systems in life-critical environments.", "url": "https://aisel.aisnet.org/pacis2026/general_topic/general_topic/21", "doi": "", "keywords": [ "clinical" ], "citations": [], "sourceId": "https://openalex.org/W7164785266", "sources": [ "OpenAlex" ] }, { "id": "OpenAlex-657874656e742d6d65643a206120", "title": "Extent-Med: A Dynamic Decision-Making Approach under Incomplete Information for Community Healthcare", "authors": "Wenwen Li", "source": "OpenAlex", "field": "Artificial Intelligence", "date": "2026-07-05", "abstract": "Large language model (LLM)-based agents have shown promise in supporting healthcare consultations, yet their effectiveness remains limited in community healthcare contexts where patients often provide incomplete, ambiguous, or non-technical descriptions of symptoms. These conditions introduce significant incomplete information and uncertainty during multi-turn consultations. To address these challenges, we introduce Extent-Med, an entropy-guided dynamic decision-making framework designed for multi-turn medical consultation under incomplete information in community healthcare. The proposed approach can structure patient narratives, grounds reasoning in external medical knowledge, and prioritizes high-information symptoms during sequential interactions. We evaluate Extent-Med on both public medical dialogue datasets and real-world scenarios. Experimental results demonstrate that our system significantly outperforms baseline LLM-based agents and knowledge-augmented variants. This research contributes to the literature on AI-enabled decision support by demonstrating how LLM-based agents can be designed to manage uncertainty in conversational healthcare settings. The findings provide practical insights for developing trustworthy AI systems for medical consultation.", "url": "https://aisel.aisnet.org/pacis2026/ishealthcare/ishealthcare/23", "doi": "", "keywords": [ "LLM", "agent", "reasoning" ], "citations": [], "sourceId": "https://openalex.org/W7164774752", "sources": [ "OpenAlex" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 自我相关性对知觉决策中自我优势效应的影响：任务相关性的调节作用", "authors": "邬思宇, 胡传鹏", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-17", "abstract": "自我优势效应指个体加工自我相关信息时更快更准确的现象。自我匹配任务被广泛用于研究自我优势，但该任务中的自我优势效应可能是自我相关性与任务相关性共同作用的结果，难以分离二者单独的效应。本研究通过两个预注册实验，让被试将随机运动点阵的运动方向或整体颜色与自我建立联结，随后依次完成匹配任务与辨别任务。实验1中，匹配任务的自我相关性与任务目标完全重合，结果发现稳定的自我优势效应；辨别任务中所需要辨别的感觉特征既与自我相关，也是任务目标，但数据提供中等程度证据支持不存在自我优势效应，可能是因为任务目标加工抑制自我相关信息。实验2进一步在辨别任务中加入自我相关性与任务目标完全独立的条件（如，自我与刺激的颜色关联，但任务目标是判断刺激的运动方向）。结果在匹配任务中仍发现稳定的自我优势效应，但辨别任务的两种条件中，结果均提供中等程度证据支持不存在自我优势效应。本研究结果表明，基于随机运动点阵即时习得的自我相关性无法自动促进认知加工，自我优势效应仅在自我相关性与任务目标完全重合时（即匹配任务）才出现。本研究为自我优势效应的产生边界条件提供新证据。", "url": "https://www.chinaxiv.org/abs/202606.00118", "doi": "10.12074/202606.00118", "keywords": [ "自我优势效应", "任务相关性", "知觉决策", "漂移扩散模型", "随机点运动任务", "认知心理学" ], "citations": [ "ChinaXiv:202606.00118", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00118v1", "ChinaXiv:202606.00118V1" ], "sourceId": "ChinaXiv:202606.00118", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00118", "versionId": "ChinaXiv:202606.00118", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=614577e3a7434254bc7a6e699ef63de7&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00118v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 基于MCMC三种抽样方法的概化理论方差分量估计准确性比较", "authors": "黎光明", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-17", "abstract": "概化理论是关于行为测量可靠性的现代心理测验理论，已被广泛应用于心理测量实践中。基于p×i和p×i×h设计，采用模拟研究和实证研究，使用MCMC三种抽样方法（M-H算法、Gibbs抽样和HMC算法）对概化理论方差分量进行估计，并比较其差异。结果表明：（1）少量数据缺失对MCMC三种抽样方法几乎无影响，MCMC对于缺失数据估计具有较强的稳健性；（2）整体上，有信息先验和经验性先验较无信息先验估计准确性更高；（3）仅HMC算法表现出“跨设计性”，在两种设计之下的估计准确性都较高，但M-H算法和Gibbs抽样却受限于h侧面的方差分量估计，估计准确性都不高；（4）若M-H算法和Gibbs抽样需要克服h侧面方差分量估计准确性不高的局限性，则须规定h ≥ 4；未来研究者在使用MCMC方法时，HMC算法更值得推荐。", "url": "https://www.chinaxiv.org/abs/202606.00117", "doi": "10.12074/202606.00117", "keywords": [ "概化理论", "方差分量估计", "MCMC方法", "M-H算法", "Gibbs抽样", "HMC算法", "心理测量" ], "citations": [ "ChinaXiv:202606.00117", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00117v1", "ChinaXiv:202606.00117V1" ], "sourceId": "ChinaXiv:202606.00117", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00117", "versionId": "ChinaXiv:202606.00117", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=fba82c07484f481781d1089b452d1a47&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00117v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "arXiv-7375706572636f6e647563746976", "title": "Superconductivity from interband coupling to ferroelectric quantum critical fluctuations in two dimensions", "authors": "Sudip Kumar Saha, Jonathan Ruhman, Avraham Klein", "source": "arXiv", "field": "Interdisciplinary", "date": "2026-06-16", "abstract": "Soft critical fluctuations associated with ferroelectric quantum phase transitions are typically transverse owing to their polar nature. This implies that the conventional density--density electron--phonon coupling to these modes is strongly suppressed, which is puzzling as a variety of materials exhibit enhanced superconductivity in the vicinity of ferroelectricity. An alternative coupling mechanism is an interband ``Stark''-like coupling that connects bands of opposite parity. In the limit where one of the bands is far in energy, these processes generate an effective quadratic (two-phonon) coupling. In contrast, when both bands lie close to the Fermi energy, the resulting interaction develops singular behavior due to the additional gapless electronic states, motivating a detailed study into the dynamics of this effective two-phonon coupling. To this end, we construct the quantum critical Eliashberg theory for a two-dimensional system across a wide range of interband gap magnitudes, near the quantum critical point. We find that the critical temperature $T_c$ is strongly enhanced relative to conventional BCS expectations. In the large-gap limit, the pairing kernel acquires higher-order logarithmic contributions, leading to a parametrically enhanced $T_c$ governed by cubic and quadratic logarithmic terms. In the small-gap regime, the pairing scale exhibits a modified BCS-like form with an enhanced dependence on the inverse square root of the dimensionless coupling constant. The enhancement is due to the dynamics of the two-phonon pairing whose infrared cutoff is set by $T_c$, resulting in a significant enhancement of superconductivity compared to three-dimensional systems, where it is set by the Fermi energy. Our results elucidate the unique dynamical properties of effective two-phonon interactions, and may be relevant to layered compounds like Td-MoTe$_2$ and doped SrTiO$_3$ membranes.", "url": "http://arxiv.org/abs/2606.18251v1", "doi": "", "keywords": [], "citations": [], "sourceId": "http://arxiv.org/abs/2606.18251v1", "sources": [ "arXiv" ] }, { "id": "arXiv-6675747572652064796e616d6963", "title": "Future Dynamic 3D Reconstruction: A 3D World Model with Disentangled Ego-Motion", "authors": "Nils Morbitzer, Jonathan Evers, Artem Savkin, Thomas Stauner, Nassir Navab, Federico Tombari, Stefano Gasperini", "source": "arXiv", "field": "Artificial Intelligence", "date": "2026-06-16", "abstract": "Forecasting the evolution of dynamic environments is crucial for autonomous agents. While generative world models have recently achieved high photorealism in 2D video synthesis by mixing ego-motion and environmental dynamics within the image plane, they exhibit physical inconsistencies, such as morphing or vanishing objects, especially over long time horizons. In this paper, we propose FR3D, a world model that predicts a persistent 3D latent representation for future dynamic 3D reconstruction. Unlike prior works that treat the world as a sequence of image-based features, FR3D explicitly decouples the 3D evolution of the scene from the agent's trajectory, treating the inferred ego-motion as a latent proxy for action. This disentanglement resolves the ambiguities between self-motion and world-motion, ensuring geometric consistency into the future. Furthermore, we introduce a teacher-student distillation strategy that leverages the spatial \"common sense\" of off-the-shelf foundation models, leading to robust zero-shot generalization. Extensive experiments demonstrate FR3D's strong performance for future dynamic 3D reconstruction from monocular observations across multiple datasets, even 2 seconds into the future. Project page: https://fr3d-wm.github.io.", "url": "http://arxiv.org/abs/2606.18250v1", "doi": "", "keywords": [ "RAG", "agent" ], "citations": [], "sourceId": "http://arxiv.org/abs/2606.18250v1", "sources": [ "arXiv" ] }, { "id": "arXiv-756e6966696564206d756c74696d", "title": "Unified Multimodal Autoregressive Modeling with Shared Context-Visual Tokenizer is Key to Unification", "authors": "Wujian Peng, Lingchen Meng, Yuxuan Cai, Xianwei Zhuang, Yuhuan Yang, Rongyao Fang, Chenfei Wu, Junyang Lin, Zuxuan Wu, Shuai Bai", "source": "arXiv", "field": "Artificial Intelligence", "date": "2026-06-16", "abstract": "Unified Multimodal Modeling aims to integrate visual understanding and generation within a single system. However, existing approaches typically rely on two disparate visual tokenizers, which splits the representation space and hinders truly unified modeling. We propose UniAR, a unified autoregressive framework where a single discrete visual tokenizer serves as the key bridge between understanding and generation, enabling a shared context in which the model can directly interpret its own generated visual tokens without additional re-encoding. UniAR adapts a pretrained vision encoder with multi-level feature fusion and a lookup-free bitwise quantization scheme, preserving both high-level semantics and low-level details while scaling the effective visual vocabulary at minimal cost. Building on this, the unified autoregressive model adopts parallel-bitwise-prediction to jointly predict spatially grouped, multi-level visual codes, substantially reducing visual sequence length and accelerating generation. Finally, a diffusion-based visual decoder operates on discrete visual tokens to decode high-fidelity images. Through large-scale pre-training, followed by supervised fine-tuning and reinforcement learning, UniAR achieves state-of-the-art performance on image generation and image editing while remaining competitive on multimodal understanding benchmarks. The project page is available at https://sharelab-sii.github.io/uniar-web.", "url": "http://arxiv.org/abs/2606.18249v1", "doi": "", "keywords": [ "multimodal", "benchmark", "vision" ], "citations": [], "sourceId": "http://arxiv.org/abs/2606.18249v1", "sources": [ "arXiv" ] }, { "id": "arXiv-76697375616c2076657269666963", "title": "Visual Verification Enables Inference-time Steering and Autonomous Policy Improvement", "authors": "Mingtong Zhang, Dhruv Shah", "source": "arXiv", "field": "Robotics", "date": "2026-06-16", "abstract": "Robots deployed in the real world should learn from their experience and improve over time. This requires a mechanism of practicing and learning from feedback. In this paper, we propose VERITAS, a generator-verifier framework for generalist robot policies for inference-time policy steering and self-improvement. We use a pre-trained generalist robot policy as a ``generator'' and pair it with a gradient-free ``visual verifier'' that evaluates actions at inference time. This framework enables inference-time steering that improves policy performance without additional training. We demonstrate that inference-time verification consistently outperforms vanilla generalists without training on additional demonstration data. Additionally, we demonstrate that the verified rollouts provide effective supervision for offline policy improvement: policies fine-tuned on verified self-generated trajectories achieve consistent performance gains. Notably, we find that post-training with verified rollouts achieves comparable efficiency to expert demonstrations, while requiring no human interventions. Our results highlight inference-time verification as a practical and scalable mechanism for improving robotic policies during deployment.", "url": "http://arxiv.org/abs/2606.18247v1", "doi": "", "keywords": [ "vision" ], "citations": [], "sourceId": "http://arxiv.org/abs/2606.18247v1", "sources": [ "arXiv" ] }, { "id": "arXiv-7661726961626c652d7769647468", "title": "Variable-Width Transformers", "authors": "Zhaofeng Wu, Oliver Sieberling, Shawn Tan, Rameswar Panda, Yury Polyanskiy, Yoon Kim", "source": "arXiv", "field": "Artificial Intelligence", "date": "2026-06-16", "abstract": "Scaling model size, specifically depth and width, has driven significant progress in transformer-based language models. However, most architectures maintain a constant width across all layers, allocating a fixed parameter and computation budget evenly despite different layers potentially playing distinct computational roles. In this work, we empirically investigate nonuniform capacity allocation across network depth by proposing a $\\times$-shaped > 以柔克刚：自我关怀与韧性关系的三水平元分析", "authors": "李忻奕, 贺嘉玺, 肖涵, 刘筱笛, 周广玉", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-16", "abstract": "自我关怀作为一种基于接纳与慈悲的自我相处之道，可能是潜在的韧性保护性因素。研究采用三水平元分析探究自我关怀与韧性的关系及其异质性。通过系统性检索与筛选，共纳入124篇文献、128个样本与296个效应量，总样本量为44,775。结果表明，自我关怀与韧性显著正相关(r = 0.46)，且自我关怀干预对韧性有显著促进作用(g = 0.49)。调节效应分析发现，自我关怀与韧性的关系受人群特征(健康状况)、情境因素(逆境与文化背景)、韧性操作化方式与研究设计的影响。不同自我关怀类型与成分对韧性的效应存在差异：非自我关怀式反应与韧性的关系相对更强；普遍人性感与韧性的关系较弱。研究建构并检验了自我关怀促进韧性的情感调节模型，支持将自我关怀作为韧性干预的核心靶点之一，并为开展精准干预与本土化干预提供了实践启示。", "url": "https://www.chinaxiv.org/abs/202606.00116", "doi": "10.12074/202606.00116", "keywords": [ "自我关怀", "韧性", "三水平元分析", "文化", "情感调节", "应用心理学" ], "citations": [ "ChinaXiv:202606.00116", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00116v1", "ChinaXiv:202606.00116V1" ], "sourceId": "ChinaXiv:202606.00116", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00116", "versionId": "ChinaXiv:202606.00116", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=cfd99319e31a40d9b74986c1a0414c2c&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00116v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 体感游戏对儿童青少年执行功能的干预效果及机制", "authors": "刘涵慧, 吴际, 葛雪景, 李会杰", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-16", "abstract": "近年来，儿童青少年身体活动不足与屏幕时间增加的问题日益突出，对其身心健康和执行功能发展产生了深远影响。体感游戏作为一种融合身体运动与认知挑战的创新干预手段，在提升儿童青少年执行功能方面展现出较大潜力。基于对体感游戏干预范式的系统梳理，本文重点探讨了体感游戏改善儿童青少年执行功能的效果及其作用机制。现有证据表明，体感游戏通过生理唤醒、认知参与和神经重塑等多重机制，显著提升了儿童青少年的抑制控制、工作记忆和认知灵活性，尤其在短期及长期干预中效果更为明显。干预效果受到年龄、执行功能基线水平、体重、游戏认知负荷、运动强度、互动方式及干预场景等多重因素的调节。相较于既有元分析，本文进一步提出了“三路径协同假设模型”，整合了生理、认知与神经机制，并系统梳理了从个体特征到环境因素的调节变量，为理解干预效果的异质性提供了统一解释框架。未来研究应着重开发个性化与定制化的体感游戏、探索体感游戏干预的“剂量-反应”关系模型、拓展虚拟现实技术的应用、增强体感游戏干预研究的外部效度，并进一步整合认知、生理与神经机制，构建统一的理论模型，从而推动体感游戏在儿童青少年认知健康促进领域的科学化与精准化应用。", "url": "https://www.chinaxiv.org/abs/202606.00115", "doi": "10.12074/202606.00115", "keywords": [ "体感游戏", "干预", "执行功能", "儿童青少年", "发展心理学" ], "citations": [ "ChinaXiv:202606.00115", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00115v1" ], "sourceId": "ChinaXiv:202606.00115", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00115", "versionId": "ChinaXiv:202606.00115", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=1fced9d4fc4c44e0a642404b626e098e&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00115v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 2004—2023年中国登革热时空分布特征与影响因素分析研究 后印本", "authors": "王稼璇, 王兆娴, 黄小芬, 赵进奎, 拉巴桑珠", "source": "ChinaXiv", "field": "医学、药学", "date": "2026-06-16", "abstract": "背景 登革热是我国蚊传疾病中发病率上升较快的媒介传染病之一，流行范围在近几年迅速向北部地区蔓延。目的 分析 2004—2023 年中国登革热的疾病负担、时空分布特征及其影响因素。方法 利用 2025 年全球疾病负担（GBD）数据库、中国公共卫生科学数据中心、《中国卫生健康统计年鉴》、国家数据及天气后报网数据库，分析中国登革热发病及死亡的年百分比变化（EAPC），描述性分析登革热发病率的时间地域分布及流行趋势，最后通过多重共线性及空间自相关检验后，利用时空地理加权回归（GTWR）模型结合 2018—2020年经济、交通、医疗卫生及自然4个维度的影响因素进行省级地域异质性分析。结果 2004—2023年中国登革热年龄标化发病率呈上升趋势（EAPC=5.51），年龄标化死亡率呈下降趋势（EAPC=-5.16）。我国大部分省市登革热发病率在 2004—2020 年间呈上升趋势，发病高峰为 9 月份。依据 2018—2020 年中国登革热发病率数据构建的 GTWR 模型，R2=0.739，Adjusted R2=0.719，AICc=340.492，能够较好地解释自变量对于登革热发病的影响。各变量拟合系数时空分布图显示全体居民人均可支配收入（元）及旅客周转量（亿人公里）在各省市与登革热发病率呈负相关关系，接待国际游客（百万人次）及平均气温在各省市与登革热发病率呈正相关关系，每千人口卫生技术人员数仅在东部经济发达省份与登革热发病率呈正相关关系，平均降水量（mm）在我国秦岭淮河以北主要与登革热发病率呈正相关关系，在秦岭淮河以南主要与登革热发病率呈负相关关系。结论 我国大部分省市登革热发病率在 2004—2020年间呈上升趋势，发病高峰为9月份。全体居民人均可支配收入（元）、及旅客周转量（亿人公里）、接待国际游客（百万人次）、每千人口卫生技术人员数、平均气温及平均降水量（mm）均对我国登革热的发病具有显著影响，但存在较强的地域异质性，因此应针对各地的具体情况制定针对性的防控措施。", "url": "https://www.chinaxiv.org/abs/202606.00090", "doi": "10.12114/j.issn.1007-9572.2026.0017", "keywords": [ "登革热", "发病率", "估计的年百分比变化", "时空分析", "时空地理加权回归", "影响因素", "临床医学" ], "citations": [ "ChinaXiv:202606.00090", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00090v1" ], "sourceId": "ChinaXiv:202606.00090", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00090", "versionId": "ChinaXiv:202606.00090", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=43a4f872744c4590bcb792de73d5c6e8&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00090v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 糖尿病行为与生活方式干预展望 后印本", "authors": "田向阳, 周迎生, 高莹", "source": "ChinaXiv", "field": "医学、药学", "date": "2026-06-16", "abstract": "行为与生活方式干预（behavioral and lifestyle interventions, BLIs）是 2 型糖尿病预防和治疗的基础，并逐渐走向定制化、剂量化、个性化和精准化。面对面干预在建立医患互信、融洽医患关系和提升行为干预效果方面是远程干预不可替代的。通过糖尿病自我管理教育与支持（diabetes self-management education and support, DSMES），指导患者进行自我管理，既能增加行为与生活方式干预的有效性，也可大幅减轻医护人员的工作负担。行为改变理论（behavioral change theory, BCT）和行为改变技术（behavioral change techniques, BCTs）可提高 BLIs 的效率，建议在 2型糖尿病防治中予以推广和应用。人工智能（AI）大模型（LLMs）在糖尿病发病风险预测、个性化生活方式指导、远程监测与自我管理和临床决策支持系统应用方面将发挥重要作用。", "url": "https://www.chinaxiv.org/abs/202606.00091", "doi": "10.12114/j.issn.1007-9572.2025.0587", "keywords": [ "行为与生活方式干预", "2 型糖尿病", "面对面干预", "自我管理教育与支持", "行为改变理论", "行为改变技术", "人工智能", "临床医学" ], "citations": [ "ChinaXiv:202606.00091", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00091v1" ], "sourceId": "ChinaXiv:202606.00091", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00091", "versionId": "ChinaXiv:202606.00091", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=c619fd1c73d044daacd68ce76caf7772&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00091v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 急性缺血性脑卒中血管内治疗无效再通影响因素及预后评估的研究进展 后印本", "authors": "罗田, 刘祖婷, 莫佳丽, 杨霞, 马海琳, 黄正龙, 万娟, 李宗, 况杰", "source": "ChinaXiv", "field": "医学、药学", "date": "2026-06-16", "abstract": "尽管近年来血管内治疗（EVT）技术的进步显著提高了急性缺血性脑卒中（AIS）患者的血管再通率，但无效再通（FR）的发生率仍然居高不下，具体而言，约半数接受 EVT 并成功实现完全再灌注的AIS患者，其 90 d功能预后依然不佳。需要强调的是，血管再通本身并非治疗终点，实现患者功能预后的实质性改善才是EVT的最终目标。为此，本文围绕FR的影响因素及风险评估进行系统综述，旨在深入剖析并明确导致FR的关键因素，以期为探索有效的干预策略及治疗靶点提供理论依据。", "url": "https://www.chinaxiv.org/abs/202606.00092", "doi": "10.12114/j.issn.1007-9572.2025.0585", "keywords": [ "急性缺血性脑卒中", "血管内治疗", "无效再通", "影响因素", "预后评估", "临床医学" ], "citations": [ "ChinaXiv:202606.00092", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00092v1" ], "sourceId": "ChinaXiv:202606.00092", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00092", "versionId": "ChinaXiv:202606.00092", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=0a358377cf28461b954ca05fbe38bf34&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00092v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 居住流动性对父母跨代际消费决策的影响：基于子女生命历程的视角", "authors": "何琼, 柳武妹, 顾峰", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-15", "abstract": "居住流动性是现代社会中日益普遍的生活经历，其对个体心理和行为的影响已受到广泛关注。然而，现有研究主要聚焦居住流动性对个体自身消费决策的影响，对其在家庭情境中、尤其是对父母为子女所做消费决策的影响关注不足。鉴于此，本研究聚焦父母居住流动性的跨代际影响，探究其对父母给子女所做消费决策和偏好的影响及其内在机理。由于父母给子女所做的消费决策涉及多方面，且在不同子女生命历程阶段面临的养育目标和决策重点存在显著差异，因此本研究从子女生命历程的视角出发，围绕幼儿期、少儿期与青少年期三个关键阶段，分别探讨父母居住流动性对父母为子女所做食物决策、教育决策和娱乐决策的影响，并进一步讨论其中的心理机制与边界条件。通过将居住流动性引入家庭与跨代际决策情境，本研究不仅拓展了居住流动性研究的理论边界，也为理解家庭消费决策的动态特征及相关实践与政策制定提供了理论参考。", "url": "https://www.chinaxiv.org/abs/202606.00114", "doi": "10.12074/202606.00114", "keywords": [ "居住流动性", "跨代际消费决策", "父母为子女做决策", "子女生命历程", "家庭消费决策", "管理心理学" ], "citations": [ "ChinaXiv:202606.00114", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00114v1" ], "sourceId": "ChinaXiv:202606.00114", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00114", "versionId": "ChinaXiv:202606.00114", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=fad12f7e926f410ab2dad2b3e018062c&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00114v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 级联衰变链方程的解空间在A型代数上的模结构", "authors": "武梦云, 刘雨喆", "source": "ChinaXiv", "field": "数学", "date": "2026-06-14", "abstract": "放射性核素依次衰变~$X_1 \\To{} X_2 \\To{} X_3 \\To{} \\cdots \\To{} X_n$~的每一步的衰变速率~$\\lambda_i(t)$~是一个时间函数。设~$N_i(t)$~表示第~$i$~种核素在时刻~$t$~的原子核数目（或浓度），则系统的动力学由一阶线性常微分方程组 \\begin{center} $\\dot{N_1} = -\\lambda_1 N_1$, $\\dot{N_i} = \\lambda_{i-1} N_{i-1} - \\lambda_i N_i$ ($i=1,2,...,n$) \\end{center} 描述，该线性常微分方程组就是级联衰变链方程，它也叫贝特曼方程。本文从表示论的角度研究~$n$~能级级联衰变链方程的解空间结构。通过将系数矩阵视为下三角矩阵代数~($\\mathbf{A}_n$ 型遗传代数)~中的元素，并利用模值函数空间的张量分解~$\\mathbf{Fun}(S,V)\\cong\\mathbf{Fun}(S,\\mathbb{F})\\otimes_{\\mathbb{F}}V$，将衰变链方程等价地改写为标准同态方程~$D_V f-(I_n\\otimes M)\\cdot f=0$，本文证明了无论衰变常数是常数还是时变函数，级联衰变链方程的齐次解空间的维数都恒等于~$n$，并且该齐次解空间具有左模结构。", "url": "https://www.chinaxiv.org/abs/202606.00104", "doi": "10.12074/202606.00104", "keywords": [ "级联衰变链", "贝特曼方程", "下三角矩阵代数", "模值同态方程", "解空间模结构", "代数与数论" ], "citations": [ "ChinaXiv:202606.00104", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00104v1" ], "sourceId": "ChinaXiv:202606.00104", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00104", "versionId": "ChinaXiv:202606.00104", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=071a4cabd5c541c7b6ea86b406b694be&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00104v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 大学新生心理状况差异分析——基于SCL-90心理健康普查数据的实证研究", "authors": "周海霞, 王炳锋", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-14", "abstract": "目的：基于社会生态系统理论，利用2018至2021年某高校大一新生心理健康的SCL-90普查数据，系统分析四年间大学新生在SCL-90九个因子上的差异，揭示COVID-19疫情前后心理健康的演变趋势及因子分化机制。方法：共纳入37871名有效参与对象，采用描述性统计、效应量Cohen's d和症状检出率进行跨年份比较，结合Graphical Lasso网络分析探讨九因子核心结构。结果：（1）SCL-90九因子均分呈\"先升后降\"的倒U型趋势，2020年达到峰值；（2）强迫症状四年中始终居各因子之首，2020年均值达8973；（3）2021年多数因子回落但仍高于2018年基线，呈\"不完全恢复\"；（4）因果网络分析揭示焦虑、抑郁和人际关系敏感为四年稳定的核心因子（Kendall τ=1.000）。结论：大学新生心理健康经历了\"基线—恶化—部分恢复\"的演变，因子分化模式反映了COVID-19对生态系统不同层级的差异化扰动。", "url": "https://www.chinaxiv.org/abs/202606.00089", "doi": "10.12074/202606.00089", "keywords": [ "SCL-90", "大学生心理健康", "COVID-19", "社会生态系统理论", "因果网络分析", "教育心理学" ], "citations": [ "ChinaXiv:202606.00089", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00089v1" ], "sourceId": "ChinaXiv:202606.00089", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00089", "versionId": "ChinaXiv:202606.00089", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=bb103e62fdf446948107f1839cab6eaf&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00089v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 人工智能心理咨询的技术接受差异：心理困扰程度的作用与机制", "authors": "符蓉, 邹宇, 丁如一, 黄嘉笙", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-11", "abstract": "[目的] 探讨心理困扰在人工智能（AI）心理咨询技术接受中的作用。 [方法] 490名被试通过问卷报告AI和心理咨询态度（前置态度）及心理困扰，并在多轮次的AI心理咨询师想象互动中完成对咨询师的即时评价。 [结果] 心理困扰负向预测了对AI心理咨询师的喜爱度、感知真实性与使用意愿，并削弱了前置态度对喜爱度、信任意愿、使用意愿和感知共情的预测作用。 [局限] 本研究主要考察想象互动后的即时评价，未来仍需在真实 AI 心理咨询使用情境中进一步验证。 [结论] AI心理健康服务推广应考虑不同困扰程度人群的技术接受，并优化即时互动体验。", "url": "https://www.chinaxiv.org/abs/202606.00088", "doi": "10.12074/202606.00088", "keywords": [ "心理困扰", "人工智能心理咨询", "技术接受", "临床与咨询心理学" ], "citations": [ "ChinaXiv:202606.00088", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00088v1" ], "sourceId": "ChinaXiv:202606.00088", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00088", "versionId": "ChinaXiv:202606.00088", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=7eca473a057c4c3f9f665da7107d2cb8&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00088v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 胰高糖素样肽-1/葡萄糖依赖性促胰岛素多肽双受体激动剂对2型糖尿病患者肌肉的影响及应对措施 后印本", "authors": "杨蓓宁, 农晰婷, 李沅贞, 李杨雪, 赵一点, 李恒", "source": "ChinaXiv", "field": "医学、药学", "date": "2026-06-11", "abstract": "肌少症是2型糖尿病患者常见的并发症，以骨骼肌量进行性减少、肌力减退及功能衰减为特征，与胰岛素抵抗、慢性炎症及代谢紊乱密切相关。替尔泊肽作为全球首个胰高糖素样肽-1（GLP-1）/葡萄糖依赖性促胰岛素多肽（GIP）双受体激动剂，通过激活GLP-1受体和GIP受体双重通路，在降糖、减重及调节代谢中展现出显著优势。近年来研究发现，替尔泊肽对2型糖尿病合并肌少症患者的肌肉存在双向影响：一方面通过减少内脏脂肪面积、改善肌肉脂肪浸润等多种机制保护肌肉；另一方面可能因体质量快速下降引发肌肉流失风险。本综述系统整合基础研究与临床证据，旨在阐明替尔泊肽对不同2型糖尿病人群肌肉成分的双向影响，探讨肌肉保护与减重的平衡，并讨论联合干预策略的临床潜力，为临床实践提供证据。", "url": "https://www.chinaxiv.org/abs/202606.00093", "doi": "10.12114/j.issn.1007-9572.2025.0571", "keywords": [ "糖尿病", "2 型", "替尔泊肽", "葡萄糖依赖性促胰岛素多肽", "胰高糖素样肽 -1 受体激动剂", "肌少症", "预防医学与公共卫生学" ], "citations": [ "ChinaXiv:202606.00093", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00093v1" ], "sourceId": "ChinaXiv:202606.00093", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00093", "versionId": "ChinaXiv:202606.00093", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=aa57cec478b74a6d8b34fdc20ea9d2ab&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00093v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 中国儿童急性淋巴细胞白血病与脂代谢紊乱的因果关联及共享遗传基础研究：基于孟德尔随机化与多组学整合 后印本", "authors": "王子怡, 彭孝成, 陈远方, 司佳, 徐酩", "source": "ChinaXiv", "field": "医学、药学", "date": "2026-06-11", "abstract": "背景 儿童急性淋巴细胞白血病（ALL）长期幸存者的脂代谢紊乱发生率显著增高，心血管疾病风险明显上升，但两者间的因果关系及共享遗传机制在东亚人群中尚待系统阐明。目的 探讨中国儿童ALL与脂代谢紊乱之间的因果关联及共享遗传基础，识别多效性基因座、功能基因及潜在治疗靶点。方法 本研究基于已发表文献授权获取的于2007年1月—2013年9月收集的中国儿童ALL全基因组关联研究汇总统计数据（纳入269例患儿及1 039名无癌对照），对1 035个东亚人群表型开展双向孟德尔随机化全表型组关联研究（MR-PheWAS），并在欧洲队列（197例ALL患者及314 192名对照）中进行验证。采用连锁不平衡分数回归与整合多效性及注释的遗传分析，评估遗传相关性与重叠程度。通过复合零假设下的多效性分析（PLACO）识别多效性基因座，并借助遗传关联的功能映射与注释（FUMA）平台进行功能注释。基于汇总数据的孟德尔随机化（SMR）筛选共享功能基因，进一步通过通路富集分析与药物-基因互作分析探索潜在治疗靶点。结果 正向MR分析显示，较高BMI、嗜酸性粒细胞计数、血小板计数及C反应蛋白水平与儿童ALL发病风险增加存在因果关联。反向MR分析提示，ALL会导致高密度脂蛋白胆固醇（HDL-C）、载脂蛋白 A、血糖及性激素结合球蛋白水平降低，并导致甘油三酯（TG）、低密度脂蛋白胆固醇和肝酶水平升高。在欧洲人群队列中的验证进一步支持了ALL与TG之间的因果关联，但效应值（OR=0.99）接近1，提示其临床意义有限。遗传学分析揭示了ALL与TG（P=1.95×10-26）及ALL与HDL-C（P=0.018）之间存在显著的遗传重叠。PLACO分析鉴定出158个多效性单核苷酸多态性（SNP），这些位点汇聚于28个独立基因座，包含LRRC16A［rs67245361，组合注释依赖型损耗（CADD）评分=16.67］与HYKK（rs11852372）等高置信度变异位点。SMR分析最终确定57个共享功能基因（如IFIT2、NPEPPS、WDR81），主要富集于免疫和代谢相关通路。药物-基因互作分析筛选出针对13个共享基因的49种候选化合物，包括靶向GPR27的埃罗妥珠单抗及靶向NPEPPS的ANTAQ。结论 本研究揭示了儿童ALL与脂代谢紊乱之间存在稳健的因果关联及共享遗传基础，为 ALL 幸存者的长期代谢健康管理与靶向治疗策略提供了新的遗传学依据与转化方向。", "url": "https://www.chinaxiv.org/abs/202606.00094", "doi": "10.12114/j.issn.1007-9572.2025.0577", "keywords": [ "急性淋巴细胞白血病", "脂代谢", "儿童：孟德尔随机化分析", "基因多效性", "药物 - 基因相互作用", "预防医学与公共卫生学" ], "citations": [ "ChinaXiv:202606.00094", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00094v1" ], "sourceId": "ChinaXiv:202606.00094", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00094", "versionId": "ChinaXiv:202606.00094", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=1dcfdda82e7349d7aaf90385666720f4&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00094v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> Optical design of wide-field and broadband light field camera for high-precision optical surface defect detection 后印本", "authors": "Chengchen Zhou, Yukun Wang, Yue Ding, Dacheng Wang, Jiucheng Nie, Jialong Li, Zhixi Li, Zheng Zhou, Shuangshuang Zhang, Xiaokun Wang", "source": "ChinaXiv", "field": "天文学", "date": "2026-06-11", "abstract": "To address the challenges of high-precision optical surface defect detection, we propose a novel design for a wide-field and broadband light field camera in this work. The proposed system can achieve a 50° field of view and operates at both visible and near-infrared wavelengths. Using the principles of light field imaging, the proposed design enables 3D reconstruction of optical surfaces, thus enabling vertical surface height measurements with enhanced accuracy. Using Zemax-based simulations, we evaluate the system’s modulation transfer function, its optical aberrations, and its tolerance to shape variations through Zernike coefficient adjustments. The results demonstrate that this camera can achieve the required spatial resolution while also maintaining high imaging quality and thus offers a promising solution for advanced optical surface defect inspection.", "url": "https://www.chinaxiv.org/abs/202606.00095", "doi": "10.61977/ati2025036", "keywords": [ "Optical design", "Defect detection", "Wide-field camera", "Broadband light field camera", "天文仪器与技术" ], "citations": [ "ChinaXiv:202606.00095", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00095v1" ], "sourceId": "ChinaXiv:202606.00095", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00095", "versionId": "ChinaXiv:202606.00095", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=c43b476c510c4f1ba4aeaa51b29dd248&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00095v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> Forecasting solar cycles using the time-series dense encoder deep learning model 后印本", "authors": "Cui Zhao, Shangbin Yang, Jianguo Liu, Shiyuan Liu", "source": "ChinaXiv", "field": "天文学", "date": "2026-06-11", "abstract": "The solar cycle (SC), a phenomenon caused by the quasi-periodic regular activities in the Sun, occurs approximately every 11 years. Intense solar activity can disrupt the Earth’s ionosphere, affecting communication and navigation systems. Consequently, accurately predicting the intensity of the SC holds great significance, but predicting the SC involves a long-term time series, and many existing time series forecasting methods have fallen short in terms of accuracy and efficiency. The Time-series Dense Encoder model is a deep learning solution tailored for long time series prediction. Based on a multi-layer perceptron structure, it outperforms the best previously existing models in accuracy, while being efficiently trainable on general datasets. We propose a method based on this model for SC forecasting. Using a trained model, we predict the test set from SC 19 to SC 25 with an average mean absolute percentage error of 32.02, root mean square error of 30.3, mean absolute error of 23.32, and R2 (coefficient of determination) of 0.76, outperforming other deep learning models in terms of accuracy and training efficiency on sunspot number datasets. Subsequently, we use it to predict the peaks of SC 25 and SC 26. For SC 25, the peak time has ended, but a stronger peak is predicted for SC 26, of 199.3, within a range of 170.8–221.9, projected to occur during April 2034.", "url": "https://www.chinaxiv.org/abs/202606.00096", "doi": "10.3724/ati2025052", "keywords": [ "Solar cycle", "Forecasting", "TiDE", "Deep learning", "天文仪器与技术" ], "citations": [ "ChinaXiv:202606.00096", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00096v1" ], "sourceId": "ChinaXiv:202606.00096", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00096", "versionId": "ChinaXiv:202606.00096", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=2bbf23295854451e8615089cadee3750&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00096v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> Optical neural networks: principles, challenges, and future prospects in computing and astrophotonics 后印本", "authors": "Xiaoqian Zhang, Huan Wang, Qichang An, Hongchao Zhao", "source": "ChinaXiv", "field": "天文学", "date": "2026-06-11", "abstract": "The rapid development of optical neural networks (ONNs) has led to the introduction of new research avenues for computing power enhancement. Because of the characteristics of optical signals, which include low power consumption, low latency, high parallelism, and large bandwidths, optical computing based on neural network architectures is showing promise for processing of spatial signals, temporal signals, and on-chip information. At present, there is a lack of a unified ONN computing architecture, and because of the limitations of the physical characteristics of these networks, different application scenarios have led to proposals of different requirements for the structural design, device selection, integration method, and signal processing method of the network. In this paper, we systematically elaborate on the practical value of ONNs, analyze their computational fundamentals in depth, discuss the challenges faced in computational and astrophotonics applications in detail, and simultaneously emphasize the important position and broad prospects of optical computing in the future information society.", "url": "https://www.chinaxiv.org/abs/202606.00097", "doi": "10.61977/ati2025031", "keywords": [ "ONNs", "Astronomy", "Artificial intelligence", "天文仪器与技术" ], "citations": [ "ChinaXiv:202606.00097", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00097v1" ], "sourceId": "ChinaXiv:202606.00097", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00097", "versionId": "ChinaXiv:202606.00097", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=15503de3360441b8a54c8d9ec8c4cead&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00097v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> Progress in VLBI observations with the Haoping 40 m radio telescope 后印本", "authors": "DeWu, JintaoLuo, YueHu, WuJiang, ZhenYan, JiaLiu, RurongChen, LangCui, YupingGao, WenChen, PingliWang, YifengLi, ZurongZhou", "source": "ChinaXiv", "field": "天文学", "date": "2026-06-11", "abstract": "Haoping 40 m radio telescope at the National Time Service Center, Chinese Academy of Sciences was built in 2014 and is primarily used to observe navigation satellites and pulsars. Since the first successful very long baseline interferometry (VLBI) observation of L-band radio source fringes in 2022, ten observations have been made so far. The stations involved in the observations include the Haoping 40 m radio telescope (Haoping), the Tianma 65m radio telescope (Tianma), the Nanshan 26 m radio telescope (Urumqi), the Guizhou 500 m radio telescope (FAST), the Jilin 13 m radio telescope (Jilin), the Effelsberg 100 m radio telescope (Effelsberg), the Onsala 25 m radio telescope (Onsala), and the Chiang Mai 40 m radio telescope (Chiang Mai). This paper presents details on the specifications of the Haoping 40 m radio telescope, as well as the design of the VLBI experiment, the observation process, and the data processing. We also discuss the analysis of the fringe results involving the Haoping 40 m radio telescope, using Distributed FX Correlator to obtain excellent results. We confirm that the telescope is capable of participating in VLBI observations and performing specific data processing tasks. It can therefore play a greater role in future VLBI observations.", "url": "https://www.chinaxiv.org/abs/202606.00098", "doi": "10.61977/ati2025035", "keywords": [ "VLBI", "Radio Telescope", "Distributed FX Correlator", "Fringe fitting", "Pulsar", "天文仪器与技术" ], "citations": [ "ChinaXiv:202606.00098", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00098v1" ], "sourceId": "ChinaXiv:202606.00098", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00098", "versionId": "ChinaXiv:202606.00098", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=dbb360919e374261ac0a4edd3e3d1a7e&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00098v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 职业人群石油工人相对脂肪量指数长期变化趋势与高血压风险的关系：基于石油工人的性别的纵向轨迹建模研究 后印本", "authors": "王崛起, 姜苏芯, 关雪, 陶宁", "source": "ChinaXiv", "field": "医学、药学", "date": "2026-06-11", "abstract": "背景 石油工人因长期暴露于高温、噪声和化学物质等特殊环境，面临更高的肥胖和心血管疾病风险，亟需针对性研究。然而，针对该人群相对脂肪量（RFM）指数与高血压风险的研究尚不充分。本研究以中国新疆维吾尔自治区石油工业工人为对象，探讨RFM指数长期变化趋势与高血压风险的关系，采用组轨迹模型（GBTM）方法，以期为该群体健康管理提供科学支持。方法 选取2020年1月—2023年12月于新疆克拉玛依某中心医院连续体检的1 560名石油工人。通过体检系统收集基线数据，采用随机森林筛选前8位协变量，基于石油工人RFM指数及其四分位数分组行二元Logistic回归分析计算高血压风险的OR及95%CI，并分析体力活动与倒班的在RFM指数于高血压风险的中介效应。运用GBTM识别2020—2023年RFM指数纵向轨迹分组，并采用多因素Logistic回归分析评估不同轨迹组的高血压风险。结果 本研究共纳入1 560名石油工人，其中女543名，男1 017名。以石油工人RFM指数及其四分位数分组为自变量，进行二元Logistics回归分析，结果显示显示无论性别，石油工人RFM指数均与高血压风险呈正相关（P<0.05）；石油工人中介分析中，体力活动在女性与男性之间分别介导了30.9%、9.08%的和RFM指数与高血压之间的关联；此外，轮班工作在女性与男性中分别介导了20.4%和18.45%的RFM指数与高血压之间的关联。GBTM分析识别如下RFM指数纵向轨迹分组：女性低稳定组（n=194，35.73%）、中稳定组（n=250，46.04%）和高稳定组（n=99，18.23%）；男性低稳定组（n=337，33.13%）、中稳定组（n=427，41.99%）和高稳定组（n=253，24.88%）。多因素Logistic回归分析结果显示，与RFM指数轨迹低稳定组相比，在女性的高稳定组高血压风险的OR为13.39（4.38~40.94）；男性高稳定组高血压风险的OR为2.40（1.65~3.49）。结论 石油工人长期过高的RFM值与高血压风险显著相关，且该关联在女性中更为明显，提示可应推动对石油工人这类高风险职业人群的体脂管理，以降低高血压发生的风险。", "url": "https://www.chinaxiv.org/abs/202606.00099", "doi": "10.12114/j.issn.1007-9572.2025.0304", "keywords": [ "高血压", "石油工人", "相对脂肪量指数", "组轨迹模型", "纵向研究", "预防医学与公共卫生学" ], "citations": [ "ChinaXiv:202606.00099", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00099v1" ], "sourceId": "ChinaXiv:202606.00099", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00099", "versionId": "ChinaXiv:202606.00099", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=7f7a8280dd93471180456261fa355c26&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00099v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> A dual-power supply system for the Solar Close Observations and Proximity Experiments (SCOPE) mission 后印本", "authors": "Ziyuan Wang, Jiang Tian, Zhenhua Ge, Jing Feng", "source": "ChinaXiv", "field": "天文学", "date": "2026-06-11", "abstract": "Previous solar probes have relied on solar energy for power, but in the near-solar environment, traditional solar panels are prone to overheating and radiation damage, increasing system complexity and reducing power reliability. This study introduces a dual-power system integrating solar-thermal thermoelectric generation with photovoltaic technology. First, suitable thermoelectric materials are screened, the geometric structure of the thermoelectric devices is simulated, and then the fabricated thermoelectric devices are subjected to cyclic heating-cooling power generation tests and long-duration high-temperature power generation tests. The results demonstrate that a single thermoelectric device can stably provide 3.5 W of power with excellent cycling stability. Additionally, this study discusses design concepts for energy storage and intelligent energy management systems required by the dual-power system. Designed for the Solar Close Observations and Proximity Experiments (SCOPE) mission, this dual-power supply system integrates the benefits of both to address demands under varying environmental conditions.", "url": "https://www.chinaxiv.org/abs/202606.00100", "doi": "10.61977/ati2025042", "keywords": [ "SCOPE", "Thermoelectric generation", "Dual-power design", "天文仪器与技术" ], "citations": [ "ChinaXiv:202606.00100", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00100v1" ], "sourceId": "ChinaXiv:202606.00100", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00100", "versionId": "ChinaXiv:202606.00100", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=4e6b524983d9431e8a830db4ec5d77df&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00100v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> Optical design of an image slicer for the low-dispersion spectrograph of the Chinese Giant Solar Telescope 后印本", "authors": "Dingjun Wang, Liang Chang", "source": "ChinaXiv", "field": "天文学", "date": "2026-06-11", "abstract": "The Chinese Giant Solar Telescope (CGST) low-dispersion spectrograph requires a large field-of-view (FOV) and high spatial resolution, which can be addressed by a carefully designed image slicer system. Our proposed design divides the rectangular 50ʹʹ × 20ʹʹ FOV at the telescope focal plane into four 50ʹʹ × 5ʹʹ subfields. Each subfield undergoes optical reconstruction using its independent collimator-camera system (F/36–F/25.79), achieving vertical alignment and focal reduction of subfields to form a pseudo-slit. Using tilt mirrors for scanning allows simultaneous acquisition of spectral data with both a large FOV and a high angular resolution of 0.05ʹʹ. This resolves manufacturing challenges for an image slicer, avoiding the requirement for hundreds of elements, multi-angle configurations, and compact dimensions, and also provides effective technical support for engineering work on the CGST.", "url": "https://www.chinaxiv.org/abs/202606.00101", "doi": "10.61977/ati2025040", "keywords": [ "Image slicer", "CGST", "Integral field spectrograph", "Spatial resolution", "天文仪器与技术" ], "citations": [ "ChinaXiv:202606.00101", "CSTR:.cn", "https://www.chinaxiv.org/abs/202606.00101v1" ], "sourceId": "ChinaXiv:202606.00101", "chinaXiv": { "canonicalId": "ChinaXiv:202606.00101", "versionId": "ChinaXiv:202606.00101", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=5693ecf226f44598a492655284c3fd2b&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202606.00101v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323531", "title": "网络首发 --> 人际趋近-回避动作对联合Flanker效应的调节", "authors": "赵梦飞, 白琳瑜, 沈模卫, 汪俊", "source": "ChinaXiv", "field": "心理学", "date": "2026-06-05", "abstract": "本研究旨在探讨社会情境下人际具身动作对联合行动的调节作用。以往研究多集中于个体水平的具身效应，缺乏对社会情境中人际具身效应的探讨。本研究结合人际趋近-回避动作与联合Flanker任务，通过一系列实验系统考察人际具身动作对联合行动效应的调节作用，并检验同伴社会属性与互动有效性的作用。实验1a与1b表明，人际趋近动作可显著缩短人际距离感知并增强联合Flanker效应，而回避动作则增加人际距离感知并使联合Flanker效应消失。实验2a和2b进一步表明，具身动作的调节作用仅在同伴具有社会属性且双方形成有效互动时出现。综上所述，人际趋近-回避动作可调节联合行动效应，但人际具身效应依赖于同伴的社会属性及互动有效性。该研究揭示了人际具身效应在联合行动中的重要作用，为进一步理解联合行动提供了具身理论框架。", "url": "https://www.chinaxiv.org/abs/202510.00079", "doi": "10.12074/202510.00079", "keywords": [ "联合行动", "具身认知", "人际距离", "趋近-回避动作", "认知心理学" ], "citations": [ "ChinaXiv:202510.00079", "CSTR:.cn", "https://www.chinaxiv.org/abs/202510.00079v2", "https://www.chinaxiv.org/abs/202510.00079v1" ], "sourceId": "ChinaXiv:202510.00079", "chinaXiv": { "canonicalId": "ChinaXiv:202510.00079", "versionId": "ChinaXiv:202510.00079", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=ddc93d31174340dcbb8ab90bc035a1f3&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202510.00079v2", "https://www.chinaxiv.org/abs/202510.00079v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "bioRxiv-666574616c206d72692072657665", "title": "Fetal MRI reveals altered prenatal cortical surface area in fetuses later diagnosed with autism spectrum disorder", "authors": "Gondova, A.; Saucedo Olvera, S.; Qiu, Y.; Guo, H.; Jeong, S.; Chung, W. K.; Grant, E. P.; Kong, X.-J.; Im, K.", "source": "bioRxiv", "field": "Interdisciplinary", "date": "2026-06-03", "abstract": "Autism spectrum disorder (ASD) is increasingly conceptualized as a condition rooted in altered prenatal neurodevelopment, yet in vivo evidence from fetal brain imaging remains limited. Using retrospective fetal MRI and surface-based morphometry, we investigated cortical development in 15 fetuses later diagnosed with ASD (77%; mean gestational age [GA] = 26.7 weeks) without major structural brain abnormalities and compared them with 60 typically developing controls (57% male; mean GA = 28.4 weeks). Fetuses later diagnosed with ASD showed significantly reduced whole-brain inner cortical plate surface area compared with controls ({beta} = -0.08 {+/-} 0.02 SE, p = 0.002, partial {superscript 2} = 0.13), corresponding to an estimated [~]7.7% reduction (predicted at GA = 28.1 weeks). Lobar mixed-effects analyses demonstrated broadly distributed reductions across all cortical lobes (FDR-corrected p = <0.001-0.024; Cohens d = -0.06 to -0.10), with modest regional heterogeneity indicating relatively greater frontal and insular involvement (groupxlobe: F = 19.31, p = 0.002, {superscript 2} = 0.08). Surface area findings remained directionally stable across sensitivity analyses, including restriction to neurodevelopmentally confirmed controls and models accounting for image quality variability, although effect sizes were attenuated after quality adjustment. Normative modeling further demonstrated subtle negative deviations from typical prenatal cortical surface area trajectories in ASD (mean Z = -0.27, p = 0.018). These findings suggest that aspects of cortical morphogenesis may diverge prenatally in individuals later diagnosed with ASD and suggest the feasibility of fetal MRI-based surface morphometry for studying early neurodevelopmental variation associated with ASD risk.", "url": "https://doi.org/10.64898/2026.06.01.729342", "doi": "10.64898/2026.06.01.729342", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.729342", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-6d756c74692d6f6d69637320616e", "title": "Multi-omics analysis reveals chromatin and transcriptomic remodeling in hippocampal CA1 following adolescent social isolation", "authors": "Kubota, A.; Shinohara, Y.; Goto, A.; Tajima, A.", "source": "bioRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "Social isolation (SI) during adolescence is associated with long-term vulnerability to psychiatric disorders; however, its effect on the hippocampal epigenome and transcriptome remains unclear. Here, we performed integrative ATAC-seq and RNA-seq of the hippocampal CA1 region using an adolescent mouse SI model, combined with single-cell RNA-seq reference mapping and cell type deconvolution. ATAC-seq identified SI-associated alterations in chromatin accessibility, including an increase in enhancer-associated regions linked to calcium transport and a decrease in promoter regions related to synaptic organization. Motif enrichment analysis highlighted that the activator protein 1 (AP-1) motif within these regions exhibited reduced accessibility. RNA-seq identified 106 differentially expressed genes, including the upregulation of Fosl2 and Hdac9 and the downregulation of Fbxw7, along with the enrichment of myelination-related pathways. Although global concordance between chromatin accessibility and transcriptional changes is limited, integrative multi-omics revealed locally coordinated shifts across a subset of differentially expressed genes. Cell type-oriented analyses suggested that SI-downregulated transcriptional signatures were preferentially linked to excitatory neurons, whereas SI-upregulated signatures were enriched in non-neuronal populations, particularly oligodendrocytes. Consistent with this finding, deconvolution indicated an increased representation of oligodendrocytes along with a reduction in excitatory neurons in isolated mice. Together, these findings suggest that adolescent SI drives selective epigenomic and transcriptional remodeling within the hippocampal CA1 circuits, accompanied by divergent adaptive responses across neuronal and glial populations. Graphical abstract O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=200 SRC=\"FIGDIR/small/729282v1_ufig1.gif\" ALT=\"Figure 1\"> View larger version (64K): org.highwire.dtl.DTLVardef@1831b3borg.highwire.dtl.DTLVardef@70f7aforg.highwire.dtl.DTLVardef@95067dorg.highwire.dtl.DTLVardef@1dd1176_HPS_FORMAT_FIGEXP M_FIG C_FIG", "url": "https://doi.org/10.64898/2026.06.01.729282", "doi": "10.64898/2026.06.01.729282", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.729282", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-63617573616c20696e666572656e", "title": "Causal inference clarifies the roles of background selection and mutation rate variation in shaping human genetic diversity", "authors": "Barroso, G. V.; Collier, N. W.; Di, C.; Lohmueller, K. E.; Ragsdale, A. P.", "source": "bioRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "Decades of theoretical and empirical work have struggled to reconcile competing views on how evolution shapes patterns of genetic variation. We now understand the genome as a mosaic molded by both neutral and selective forces, but quantifying their relative contributions remains an open challenge. A major obstacle has been the tendency to analyze each evolutionary process in isolation. But different processes may leave similar signatures on genetic variation, making it challenging to draw conclusions from correlations alone. To address this gap, we make predictions of the landscape of diversity based on background selection and mutation rate variation. We then develop structural equation models describing how mutation, recombination and selection jointly shape the genomic landscape of diversity. This approach offers a more realistic representation of biological interactions and enables rigorous evaluation of hypothesized causal structures, marking both conceptual and practical improvements over previous studies. Analyses of human data reveal large variation in the explanatory power of candidate models across chromosomes. We find that previous studies likely overestimated the predictive accuracy of background selection; although it emerges as the overall main driver of diversity, in some chromosomes mutation rate variation has a comparable impact. We also show that recombination increases diversity more strongly through its influence on background selection than through its mutagenic effect, resolving a longstanding debate. This work demonstrates that modeling variation inherent in genome biology substantially improves our ability to explain human genetic diversity. At the same time, evidence for unmodeled covariance between mutation rates and density of constrained sites reinvigorates an ongoing discussion about the evolution of the mutation landscape, although additional work is needed to determine its origins. SignificanceUnderstanding the mechanisms that create and maintain genetic diversity is fundamental to explaining how populations evolve. Early work emphasized the role of linked selection, but this focus has obscured the contributions of other processes. To overcome this limitation, we introduce structural equation models that encode the causal relationships among mutation, recombination, and selection. We find that background selection is the primary driver of genetic diversity, but its predictive power has likely been overstated in previous studies. Meanwhile, mutation rate variation substantially impacts diversity in some chromosomes. We also identify mismatches between model expectations and observed data that point to limitations in current genomic maps or to the inadequacy of background selection as the unique mode of linked selection in humans. Resolving this conflict will require integrating improved genomic resources-such as epigenetic profiles and trio-based mutation maps-into causal models like those we introduce here.", "url": "https://doi.org/10.64898/2026.06.02.727906", "doi": "10.64898/2026.06.02.727906", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.02.727906", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-61207265642d656d697474696e67", "title": "A red-emitting, genetically encoded indicator for two-photon voltage recording in vivo", "authors": "Yang, S.; McDonald, A. J.; Lu, X.; Villette, V.; Hakam, N.; Galdamez, M.; Torne-Srivastava, T.; Foran, G.; Dong, X.; Shorey, M.; Bavili, N.; Lai, S.; Liu, Z.; Liu, H.; Maslianitsyna, T.; Fournel, R.; Ronzitti, E.; Zhu, J.; Natan, R. G.; Bradley, J.; Gaspar Santos, D.; Shan, Y.-Y. Y.; Ran, L. F.; Hu, M.; Emiliani, V.; Ji, N.; Reimer, J.; Bourdieu, L.; St-Pierre, F.", "source": "bioRxiv", "field": "Artificial Intelligence", "date": "2026-06-03", "abstract": "Genetically encoded voltage indicators (GEVIs) enable minimally invasive, cell-type-specific optical measurements of neuronal membrane potential with millisecond temporal resolution. Red-shifted GEVIs are especially advantageous because they permit spectral multiplexing with complementary sensors and enable all-optical circuit interrogation in combination with blue-light-activated opsins. Despite these advantages, existing red GEVIs remain poorly suited for in vivo use due to limited performance under two-photon (2P) excitation, the predominant modality for deep-tissue imaging. Here, we introduce VADER1, a red GEVI that overcomes this limitation and enables reliable spike detection in vivo under 2P illumination. Under 2P excitation, VADER1 supports extended voltage imaging with both random-access and resonant-scanning microscopy, enables recordings from neurons as deep as cortical layer 5, and allows dual-color imaging with calcium indicators. By filling a critical spectral gap, VADER1 enables integrated optical measurements of fast electrical activity alongside other neural signals and establishes a foundation for two-photon all-optical electrophysiology.", "url": "https://doi.org/10.64898/2026.06.01.726307", "doi": "10.64898/2026.06.01.726307", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.726307", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-7374727563747572616c20646972", "title": "Structural Directional Brain Behavior Asymmetry Across Cortical and Non-Cortical Regions", "authors": "Hashemi, F.; Momtaz, H.; Malekzadeh, M.; Kashani, A.", "source": "bioRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "A substantial body of research suggests that the left and right cerebral hemispheres play differential roles in shaping human behavior. However, due to methodological considerations, most studies in this field have relied primarily on psychological methods. Here, we present exploratory neurobiological evidence suggesting that brain volume across numerous cortical and non-cortical homotopic regions may display consistent directional asymmetry in relation to a wide range of behavioral measures. Of particular note, such asymmetry recurred between contralateral homotopic areas across many behavioral parameters. The asymmetric behavioral directionality is distributed across most regions of the human brain, especially in the frontal and temporal cortices, which are particularly developed in humans. This may add a new dimension to previously described aspects of hemispheric asymmetry. In addition, it may help to understand why a marked functional asymmetry can be observed even when structural asymmetry is subtle. Moreover, these findings may shed light on how the brain modulates behavior in health and disease and may contribute to understanding processes involved in neurological and psychiatric disorders.", "url": "https://doi.org/10.64898/2026.06.02.729666", "doi": "10.64898/2026.06.02.729666", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.02.729666", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-6162657272616e74206368726f6d", "title": "Aberrant chromatin remodeling influences human neural cell fate change in Trisomy 21", "authors": "Klein, J. A.; Upadhya, S.; Nathanson, A.; Silvian, D.; Zaniewski, E. F.; Morris, R.; Haas, W.; Barrett, L.", "source": "bioRxiv", "field": "Artificial Intelligence", "date": "2026-06-03", "abstract": "Correct neural progenitor cell (NPC) fate specification is essential to produce the full complement of neurons and glia needed for proper brain structure and function. Neurodevelopmental disorders, including the autosomal aneuploidy Down syndrome (DS), or Trisomy 21 (T21), are frequently associated with impaired cell fate decisions which ultimately drive differences in overall brain size and cell type composition through unknown mechanisms. To uncover mechanisms driving altered NPC fate in T21, we leverage paired single-nuclei transcriptomic and epigenomic analyses of human induced pluripotent stem cell (iPSC)-derived NPCs and their differentiated progeny coupled with in depth clonal cell fate, cell cycle, and proteomic analyses. Here we show that T21 NPCs fail to activate an orchestrated neurogenic program during the earliest stages of fate specification, instead maintaining a repressive chromatin structure over neurogenic loci, leading to reduced neurogenesis and continued NPC proliferation. We identify novel enrichment of the repressive histone mark H3K27me3 at fate instructive genes dysregulated across diverse cell and tissue types in T21, with corresponding genome-wide changes in H3K27me3 binding in T21 NPCs. Moreover, pharmacological treatment with an inhibitor of the Polycomb repressive complex 2 (PRC2) which catalyzes H3K27 methylation, is sufficient to partially restore neurogenesis in T21 cells. Collectively, our analyses reveal a chromatin mechanism influencing neurogenic defects in T21.", "url": "https://doi.org/10.64898/2026.06.01.729170", "doi": "10.64898/2026.06.01.729170", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.729170", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-73686f72742d7465726d20646576", "title": "Short-Term Developmental Trajectories of Dorsal-Ventral Pathways and Their Relationships with First-Grade Learning", "authors": "Ren, X.; Booth, J. R.; Amorosino, G.; Pestilli, F.; Vinci-Booher, S.", "source": "bioRxiv", "field": "Interdisciplinary", "date": "2026-06-03", "abstract": "The first year of formal schooling is a year of foundational reading and math learning, and individual differences emerging within this single year predict academic achievement decades later. Yet, how brain changes throughout this critical year relate to individual differences in reading and math learning remains uncharacterized. In this pre-registered study (https://osf.io/97ybe), we acquired monthly both behavioral assessments of reading- and math-learning, and diffusion-weighted MRI scans to measure white matter microstructure, across the first-grade year. Behavioral learning trajectories follow either a sigmoid for reading or an inverted-U for math. Month-to-month microstructural changes in the right middle longitudinal fasciculus predicted corresponding changes in math performance, but not in reading. Findings highlight white matter microstructure as a dynamic substrate of early math learning, and reveal a more general principle: rapid changes in white-matter microstructure during the foundational learning window may be associated with distinct academic domains.", "url": "https://doi.org/10.64898/2026.06.02.729623", "doi": "10.64898/2026.06.02.729623", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.02.729623", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-7472616e7363726970746f6d6963", "title": "Transcriptomic profiling of the human habenula reveals a shared molecular architecture across mood disorders", "authors": "Cameron, S.; Maddock, M. L.; Walpole, S.; Weston-Green, K.; Newell, K. A.", "source": "bioRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "The habenula is a critical regulator of monoaminergic and reward circuitry and is increasingly implicated in the neurobiology of mood disorders. Preclinical studies demonstrate that habenula hyperactivity drives depressive-like behaviours and can be reversed by interventions such as ketamine and deep brain stimulation. However, the molecular architecture of the human habenula remains largely unexplored. Here, we applied a transdiagnostic framework to characterise shared and disorder-specific transcriptomic alterations across affective illness. Bulk RNA sequencing was performed on postmortem habenula-enriched tissue from controls (n = 6), major depressive disorder (MDD; n = 6), and bipolar disorder (BPD; n = 6) cases from the Netherlands Brain Bank. Differential gene expression and differential transcript usage (DTU) analyses identified diagnosis- and sex-associated transcriptional changes. Individual diagnostic comparisons revealed modest numbers of differentially expressed genes (MDD: 60; BPD: 66; FDR < 0.05), consistent with limited power and/or subtle disorder-specific effects. In contrast, transdiagnostic analysis combining affective cases (MDD + BPD; n = 12) identified 378 differentially expressed genes, indicating a robust shared molecular signature across mood disorders. Upregulated genes were enriched for potassium channel activity, calcium homeostasis, and Wnt signalling, consistent with altered neuronal excitability, while downregulated genes were enriched for metal ion binding. DTU analysis identified 49 isoform switches, highlighting isoform-specific regulation not captured at the gene level. Biological sex contributed substantially to transcriptomic variation, with 67 differentially expressed genes and 18 isoform switches differing between males and females, including sex-dependent regulation of GPR151, NLGN3, and KIF17, genes known to influence neuronal excitability. Together, these findings support a shared molecular architecture across mood disorders and underscore the importance of transdiagnostic and sex-informed approaches.", "url": "https://doi.org/10.64898/2026.06.01.728671", "doi": "10.64898/2026.06.01.728671", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.728671", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-617474656e756174656420616461", "title": "Attenuated adaptive growth of interpersonal synchrony in autism", "authors": "Kwon, J.; Kotani, H.", "source": "bioRxiv", "field": "Artificial Intelligence", "date": "2026-06-03", "abstract": "During social interactions, people continuously align their movements and rhythms, a process known as interpersonal synchrony that supports rapport, mutual understanding, and smooth communication. In autism spectrum disorder (ASD), previous studies have often reported atypical or reduced synchrony, but most have relied on aggregate or session-averaged measures that may miss how coordination develops over time. It therefore remains unclear whether interactional differences in autism reflect a general reduction in synchrony or altered temporal dynamics of interpersonal coordination. We examined the temporal dynamics of head-movement synchrony during a structured face-to-face communication task, comparing non-autistic dyads (two typically developing [TD] partners) with mixed-neurotype dyads (one TD speaker paired with one autistic listener), using gyroscope-based tracking and time-resolved trajectory modelling. Phase-based synchrony, indexed by the phase-locking value (PLV), was lower overall in mixed-neurotype dyads. Critically, time-resolved analyses revealed a marked group difference in synchrony trajectories: non-autistic dyads showed progressive, adaptive growth in synchrony over the interaction, whereas mixed-neurotype dyads showed a significantly attenuated, flatter pattern. These findings suggest that autism may involve altered temporal organization of social coordination rather than simply reduced synchrony overall. Lay AbstractWhen we talk with someone, we often naturally match their body language and rhythms without even realizing it. This physical \"syncing up\" helps us feel connected, builds trust and shared understanding, and makes communication flow easily. Research shows that autistic people might sync their movements differently during conversations compared to non-autistic people. However, past studies usually just measured an overall average of this syncing across a whole interaction. This approach misses how human interactions actually unfold over time. We wanted to know: do autistic people just sync less overall, or does their syncing change differently as the conversation goes on? To find out, we used small motion sensors to track the head movements of adults having structured face-to-face conversations and compared two types of pairs: non-autistic pairs, where both people were non-autistic, and mixed-neurotype pairs, where one non-autistic speaker talked to one autistic listener. We found a notable difference in how the two groups interacted over time. For the non-autistic pairs, the physical syncing grew progressively stronger as the conversation progressed; they progressively \"tuned in\" to each other. In contrast, mixed-neurotype pairs showed a flatter pattern--their level of syncing stayed relatively constant from start to finish without that same gradual build-up. These findings are important because they suggest that differences in autistic communication are not simply a \"lack\" or \"deficit\" in social coordination. Instead, autistic individuals have a distinct style of interacting--one that maintains social engagement without relying on the progressive build-up of physical syncing that non-autistic people use. Taken together, our results highlight the importance of examining how interactions evolve over time to better understand the different ways autistic and non-autistic people communicate.", "url": "https://doi.org/10.64898/2026.06.02.729457", "doi": "10.64898/2026.06.02.729457", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.02.729457", "sources": [ "bioRxiv" ] }, { "id": "bioRxiv-73706174696f74656d706f72616c", "title": "Spatiotemporal Decoding of Explore-Exploit Decisions in the Human Brain", "authors": "Yadav, R.; Romero, J. D.; Stephen, J. M.; Houck, J. M.; Cavanagh, J. F.; Costa, V. D.; Hogeveen, J.", "source": "bioRxiv", "field": "Artificial Intelligence", "date": "2026-06-03", "abstract": "Adaptive behavior requires flexibly shifting between exploiting familiar rewards and exploring novel opportunities. These explore-exploit decisions are implemented via a distributed brain network--anchored in frontopolar cortex (FPC) and ventromedial prefrontal cortex (vmPFC)--that computes the total value of a given choice by weighting the immediate value of familiar options against the latent future value of exploration. Capturing the precise temporal dynamics of these neural computations across spatially distributed cortical networks is critical to resolving how the brain manages this tradeoff. Here, we combined magnetoencephalography (MEG) with partially observable Markov decision process (POMDP) modeling during a reinforcement learning task. By decoding POMDP-derived choice policies in MEG source space, we mapped the precise spatiotemporal emergence of explore-exploit decisions across the cortex. We demonstrate that explore-exploit policy implementation unfolds via a hierarchical functional dissociation across the rostral prefrontal cortex. During decision formation, the lateral FPC initiates the strategic shift toward exploration hundreds of milliseconds before choice execution. Conversely, vmPFC and orbitofrontal cortex (OFC) do not exhibit early significant divergence from the baseline exploitative trace on exploration trials, displaying only a delayed, transient peak prior to choice execution. Following feedback, the vmPFC and OFC transition to a sustained representation of the choices empirical value to update reward expectancies and guide future actions. Mapping reinforcement learning variables onto millisecond-resolved neural data reveals how the human brain resolves the explore-exploit dilemma: through early strategic initiation of exploration in the FPC, a delayed exploratory shift in vmPFC and OFC, and sustained outcome evaluation to optimize future actions.", "url": "https://doi.org/10.64898/2026.06.01.729427", "doi": "10.64898/2026.06.01.729427", "keywords": [ "bioinformatics", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.729427", "sources": [ "bioRxiv" ] }, { "id": "medRxiv-6120362d6974656d20646961676e", "title": "A 6-Item Diagnostic Screener for Childbirth-Related PTSD", "authors": "Bartal, A.; Allouche-Kam, H.; Elhasid Felsenstein, T.; Dassopoulos, E. C.; Lee, M. C.; Edlow, A. G.; Orr, S. P.; Dekel, S.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "Posttraumatic stress disorder (PTSD) after traumatic childbirth is a serious maternal morbidity that affects about 20% of women following medically complicated deliveries. Yet it often goes undetected in perinatal care, in part because brief screening tools suitable for busy obstetric settings are lacking. We developed and evaluated a brief screener derived from the 20-item PTSD Checklist for DSM-5 (PCL-5) to detect childbirth-related PTSD. Women with traumatic childbirth experiences completed the PCL-5 and the gold-standard Clinician-Administered PTSD Scale for DSM-5 (CAPS-5); depression symptoms were assessed with the Edinburgh Postnatal Depression Scale (EPDS). Bootstrap resampling with LASSO regression identified the PCL-5 items most strongly associated with PTSD, and Firth logistic regression was used to estimate diagnostic accuracy. A statistically derived 6-item version of the PCL-5 (PCL-5-R6) showed excellent discrimination against clinician diagnosis (AUC = 0.95; 95% CI, 0.89-1.00). A cut-off score of 7 yielded high sensitivity (0.96) and good specificity (0.83), with overall diagnostic efficiency of 0.86. The PCL-5-R6 correlated only moderately with EPDS scores ({rho} = 0.53), indicating that depression screening alone does not reliably detect PTSD. This brief tool can offer a valid and practical approach for routine postpartum PTSD screening.", "url": "https://doi.org/10.64898/2026.03.05.26347629", "doi": "10.64898/2026.03.05.26347629", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.03.05.26347629", "sources": [ "medRxiv" ] }, { "id": "medRxiv-7472616e736c6174696e67203364", "title": "Translating 3D Slicer into Brazilian Portuguese: A methodological approach to software localization in Latin America", "authors": "Veiga, P. E. d. B.; Murta, L. O.; Goncalves, D. S.; Silva, L. S.; Montano-Serrano, V. M.; Laredo, E. H.; Lasso, A.; Pieper, S.; Gonzalez, A. V.; Pujol, S.", "source": "medRxiv", "field": "Computer Science", "date": "2026-06-03", "abstract": "3D Slicer is an open-source software platform for the analysis, segmentation, and three-dimensional visualization of medical imaging data. Although the platform is used by an international research community, its interface was historically available primarily in English, which may limit accessibility for non-English-speaking users. This study describes the development of an ad hoc methodology for the Brazilian Portuguese localization of 3D Slicer within the broader Latin American localization initiative. The methodology addresses recurrent linguistic challenges identified in a preliminary corpus of 300 interface strings, including domain-specific vocabulary, acronyms, word order, passive voice, syntagms, and the adaptation of technical terms. The translation process emphasizes textual uniformity, cohesion, terminological accuracy, and contextual validation in biomedical-computational environments. The proposed framework may support similar software localization efforts in other non-English-speaking contexts, especially when technical precision and linguistic adaptation must be balanced.", "url": "https://doi.org/10.1101/2025.09.15.25335771", "doi": "10.1101/2025.09.15.25335771", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.1101/2025.09.15.25335771", "sources": [ "medRxiv" ] }, { "id": "medRxiv-70617469656e742d737065636966", "title": "Patient-specific in silico prediction of outcomes of partial continuous-flow LVAD treatment in peripartum cardiomyopathy", "authors": "Nagawa, J.; Sack, K. L.; Nchejane, N. J.; Motchon, Y. D.; Sirry, M. S.; Kraus, S.; Davies, N. H.; Ntusi, N. A.; Franz, T.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "Patients with severe peripartum cardiomyopathy (PPCM) often receive mechanical circulatory support with good outcomes. However, mechanisms underlying the functional improvements are poorly understood for patients with different PPCM characteristics. This study investigated effects of partial, continuous-flow left ventricular assist device (LVAD) support on cardiac function and mechanics in patients with different PPCM severity. Patient-specific biventricular finite element models of six patients with different PPCM severity were developed from magnetic resonance images and combined with a circulatory system model, including variable LVAD support. Ventricular function and myocardial mechanics were predicted and changes due to LVAD support were quantified. The LVAD support decreased LV myofiber stress and increased ejection fraction (EF). EF increased steadily (two patients), fluctuated (two patients), or peaked before a steady decrease (two patients) with increasing LVAD speed. Improvement due to LVAD support was greater for PPCM patients with higher disease severity than those with lower disease severity. The LVAD and native LV jointly generated stroke volume (SV) in four patients, and the LV contribution diminished with increasing LVAD speed. In the two patients with the lowest EF, the LVAD was the sole source of SV. The improvement of cardiac function and mechanics due to LVAD support in PPCM exceeds that reported for chronic heart failure due to ischemia. However, the predicted variability of the LVAD benefits with PPCM severity and mechanical support level suggests the need and potential for further studies to guide clinicians in selecting personalised treatment parameters required for optimised LVAD therapy for each PPCM patient.", "url": "https://doi.org/10.1101/2024.09.18.24313803", "doi": "10.1101/2024.09.18.24313803", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.1101/2024.09.18.24313803", "sources": [ "medRxiv" ] }, { "id": "medRxiv-706f6c79657468796c656e652061", "title": "Polyethylene and Polyvinyl Chloride Nanoplastics Accelerate Atherosclerosis Through Distinct Changes in Smooth Muscle Cell Phenotype", "authors": "Zheng, S.; Gu, W.; Zhao, Q.; Kojima, Y.; Palm, K.; Mokry, M.; Jarr, K.-U.; Gao, H.; Damiani, I.; Qin, G.; Bahia, G.; Basu, S.; Kundu, R.; Worssam, M.; Jackson, W.; Berezowitz, A.; Weldy, C.; Cheng, P.; Pasterkamp, G.; Leeper, N. J.; Kim, J. B.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "Micro- and nanoplastics (MNPs) are increasingly detected in human tissues, yet their causal contribution to cardiovascular disease remains poorly understood. Here we show that oral exposure to polyethylene (PE) and polyvinyl chloride (PVC) -- the most abundant polymers found in human atheromas -- accelerates atherosclerosis in ApoE-/- mice through distinct, polymer-specific molecular mechanisms. While both polymers increased plaque burden and reduced contractile smooth muscle cell (SMC) markers, single-cell transcriptomic profiling revealed divergent phenotypic trajectories. PE exposure drives SMCs toward a chondromyocyte-like cell (CMC) state, characterized by upregulated osteogenic signaling and markedly increased vascular calcification. Conversely, PVC exposure promotes a fibromyocyte-like program associated with altered collagen metabolism and accelerated cell migration without enhancing calcification. These distinct SMC programs are reflected in the transcriptional signatures of symptomatic human carotid plaques, suggesting clinical relevance for polymer-specific vascular remodeling. Our findings establish a causal link between common environmental plastics and accelerated atherosclerosis, demonstrating that MNP-induced vascular risk is mediated by divergent SMC fate decisions. These results provide a mechanistic framework for assessing the cardiovascular impact of global plastic pollution and identifying potential therapeutic targets to mitigate MNP-associated vascular toxicity.", "url": "https://doi.org/10.64898/2026.02.10.26345390", "doi": "10.64898/2026.02.10.26345390", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.02.10.26345390", "sources": [ "medRxiv" ] }, { "id": "medRxiv-66697273742d74696d6520636869", "title": "First-time child protection contacts from the prenatal period to age 15 among Aboriginal children born 2006-2020: a whole-population cohort study in New South Wales, Australia", "authors": "Hanly, M. J.; Newton, B.; Ahmed, T.; Payne, T.; Powell, M.; Cripps, K.; Katz, I.; Pilkington, R.; Lynch, J.; Gray, P.; Falster, K.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "BackgroundFirst Nations children are over-represented in child protection systems in Australia and other colonised countries. Here, we apply a prevention and equity lens to the use of child protection data, to inform early opportunities to support Aboriginal children and families at risk of escalating child protection contact, from pregnancy to adolescence. MethodsWe followed 15 whole-population cohorts (born 2006-2020) of Aboriginal (n=119,716) and non-Aboriginal (n=1,456,698) children in New South Wales (NSW), Australia, to December 2021, using birth and child protection datasets linked for the NSW Child E-Cohort. In each Aboriginal and non-Aboriginal cohort born 2006 to 2020, we calculated the cumulative incidence (risk) of first-time child protection contacts from the prenatal period up to age 15 years: reports to child protection, screened in reports, investigations, child protection- defined substantiations (of actual harm or risk of significant harm assessed in the investigation), and OOHC placements. Risk differences and relative risks were also calculated. FindingsBy birth, 10-15% of Aboriginal children born 2006-2020 had a first report to child protection, with 48-54% by age 5y (2006-2016 births), and 74% by age 15y (2006 births), with similar risks of screened-in reports (e.g. 68% by age 15y). The risk of first-time substantiation was 1- 5% of Aboriginal children by birth, 17-20% by 5y, and 32% by 15y, with higher risks in more contemporary cohorts. By age 1y, 3-4% of Aboriginal children born 2006-2020 had a first OOHC placement, with 7-9% by 5y, and 14% by 15y. The risk differences between Aboriginal and non-Aboriginal children were 23 and 3 percentage points for reports and OOHC by age 1y (2020 births), respectively, increasing as children age. InterpretationDespite extensive inquiries, calls for prevention and Closing the Gap targets, our study shows the lifetime risk of child protection involvement for Aboriginal families has not improved and inequities persist. These findings support the call for Aboriginal-led approaches and greater investment in early supports for First Nations children and families. Research in ContextO_ST_ABSEvidence before this studyC_ST_ABSWe searched PubMed and Medline for studies on the lifetime risk of child protection contacts among First Nations child populations, published January 2005 to May 2025. Thirteen studies reported various child protection contacts, from the perinatal period through childhood, among birth or synthetic cohorts of First Nations children, born between 1990 and 2018, created from population data sources in jurisdictions in Australia (n=5), the United States(US) (n=6), and Aotearoa/New Zealand (NZ) (n=2) (Table E1). O_TBL View this table: org.highwire.dtl.DTLVardef@1b5e32org.highwire.dtl.DTLVardef@c552d5org.highwire.dtl.DTLVardef@c13c17org.highwire.dtl.DTLVardef@5043d6org.highwire.dtl.DTLVardef@195a626_HPS_FORMAT_FIGEXP M_TBL O_FLOATNOTable E1.C_FLOATNO O_TABLECAPTIONSystematic Review Results: Details of 13 studies on the lifetime risk of child protection contacts among First Nations child populations, published January 2005 to May 2025. C_TABLECAPTION C_TBL The most recently published study included First Nations children born 2000 to 2013 in Western Australia, which quantified the risk of reports, investigations, substantiations and removals into OOHC, from age 1 to 16 years. By age 1, 12% were reported and 3% were removed into OOHC. By age 16, 52% were reported, and 14% were removed into OOHC. Prior studies of birth or synthetic cohorts of First Nations children born 1990-2018, in the USA, NZ, and South Australia showed similar results. By age 5 years, 16% to 54% for reports, 20% for investigations, 7% to 11% for substantiations and 8% for removals into OOHC. Among the five studies with cohorts followed to 18 years, 42% were reported, 28% to 50% were investigated, 9% to 27% were substantiated, 7% to 16% were removed into OOHC and 0.8% to 3.8% had termination of parental rights. Added value of this studyThis is the largest and most contemporary study to quantify the lifetime risk of child protection contact among whole-populations of First Nations children internationally. Among 15 consecutive whole-population cohorts of First Nations children in New South Wales (NSW), Australia, born 2006 to 2020, we reported--for the first time--the full spectrum of child protection contacts, from the prenatal period. By birth, 16% were reported to child protection, 14% were investigated and 5% were substantiated in the most contemporary cohort born 2020. By age 1 year, 2.8% were removed into OOHC. In the oldest cohort born 2006, 74% were reported and 14.4% removed into OOHC by age 15 years. We also reveal the magnitude of the inequity in child protection contacts between First Nations and non-Indigenous children across the lifecourse. For example, among 2006 births, the risk of first-time reports to child protection for Aboriginal and non-Aboriginal children, respectively, was 10.5% versus 1.5% by birth (risk difference (RD), 9 percentage points; risk ratio (RR), 7.0), 53% vs 16% by age five (RD, 38pp; RR, 3.4) and 74% vs 33% by age 15 (RD, 41pp; RR 2.2). Implications of all the available evidenceThis study unequivocally shows that the lifetime risk of child protection involvement in the lives of First Nations families has not reduced in more contemporary whole-population cohorts and that inequities persist. This is consistent with evidence from prior studies internationally. It is critical that First Nations-led responses and investment in early family supports must be at the centre of system reform to realise the long-called-for shift toward prevention and to re-dress the pervasive inequities experienced by First Nations children and families in colonised countries such as Australia.", "url": "https://doi.org/10.64898/2026.03.24.26349231", "doi": "10.64898/2026.03.24.26349231", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.03.24.26349231", "sources": [ "medRxiv" ] }, { "id": "medRxiv-7368617265642067656e65746963", "title": "Shared Genetic Architecture of Psychosis, Mood, and Cognition in East Asian Ancestry", "authors": "Lim, K.; Van Der Es, T.; Song, J.; Howard, D. M.; Liu, J.; Lee, J.; Chen, C.-Y.; Lam, M.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "Genomic insights into psychiatric disorders remain heavily skewed toward European populations. In European-ancestry studies, educational attainment is typically negatively genetically correlated with major depression but paradoxically positively correlated with schizophrenia, raising the question of whether these relationships generalize across ancestries. We investigated whether this cross-trait architecture extends to East Asian ancestry (EAS). Using EAS GWAS summary statistics for major depressive disorder (MDD), schizophrenia (SZ), and educational attainment (EDU), we applied multi-trait (MTAG) and pleiotropy-informed (PLEIO) analyses to characterize shared genetic architecture across these traits. Across MTAG and PLEIO analyses, we identified 32 unique genome-wide significant loci (p < 5 x 10-8), including seven novel loci revealed in depression analysis that overlapped schizophrenia-associated signals - consistent with shared cross-trait architecture. Results reinforce a convergent risk architecture for affective and psychotic disorders in this population. Fine-mapping analyses prioritized variants mapping to candidate genes, including serine/threonine kinase VRK2, nominating targets for future follow-up. Cross-trait analyses supported a positive genetic relationship between EDU and MDD (rg = 0.308, p = 9.63 x 10-17) in East Asian data, contrasting to the negative correlation typically observed in European ancestry. These findings suggest that the genetic relationship between educational attainment and psychiatric risk may not be fully transferable across ancestries. In an independent cohort of individuals at ultra-high risk for psychosis, MTAG-derived polygenic risk scores improved case-control discrimination relative to single-trait GWAS-based scores. These results underscore the importance of ancestry-specific genomic frameworks for interpreting cross-trait psychiatric architecture and improving polygenic prediction.", "url": "https://doi.org/10.64898/2026.06.01.26354666", "doi": "10.64898/2026.06.01.26354666", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.26354666", "sources": [ "medRxiv" ] }, { "id": "medRxiv-6c6f6e6769747564696e616c2072", "title": "Longitudinal Receptive-Expressive Language Profiles in Young Autistic Children", "authors": "Latreche, K.; Godel, M.; Journal, F.; Kojovic, N.; Schaer, M.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "Background & AimsLanguage development in autism is heterogeneous and strongly predicts later functioning. The balance between receptive and expressive abilities and their developmental trajectories, however, remains poorly understood. While some autistic children exhibit a relative expressive advantage (ExpAdv), others show receptive advantage (RecAdv) or a balanced profile. Prior studies report inconsistent findings and are often limited by cross-sectional designs and small samples. The present study aimed to (1) describe longitudinal trajectories of receptive and expressive language in autistic and typically developing (TD) children; (2) classify children into ExpAdv, Balanced, and RecAdv profiles across early childhood; and (3) examine the stability and transitions of these profiles over time, including associated clinical features. MethodsWe analyzed 1,174 longitudinal time points from 318 autistic children and 294 time points from 108 TD children (1.2-5.8 years) from the Geneva Autism Cohort. Receptive and expressive language were assessed with the Mullen Scales of Early Learning. Receptive-expressive balance was quantified as the ratio of receptive to expressive age equivalent scores, classifying children into ExpAdv, Balanced, and RecAdv profiles using adapted cut-offs. Mixed-effects models examined developmental trajectories, and Sankey diagrams visualized profile transitions. Autism features and adaptive behavior were compared across profiles. ResultsAutistic children displayed lower expressive and receptive language than TD peers, with receptive abilities exceeding expressive skills in both groups. Overall, 30-35% of autistic children were classified as ExpAdv at 18-36 months, declining to [~]12% by 48-54 months, while Balanced and RecAdv profiles became more prevalent with age. ExpAdv was associated with slower verbal and non-verbal developmental gains. Stability was highest for Balanced and RecAdv profiles (50-60%), whereas ExpAdv often transitioned to Balanced. Autistic children with stable ExpAdv profiles were more often female, less likely to receive early intervention, and showed weaker adaptive communication. ConclusionsReceptive-expressive language profiles in autistic children are dynamic. ExpAdv profile is more frequent in younger autistic children, less stable, and linked to slower verbal and non-verbal development and higher autism severity. ImplicationsExpAdv may represent an early marker of autism associated with slower expressive and receptive language growth. Longitudinal monitoring of receptive and expressive skills is essential, as transitions toward Balanced or RecAdv profiles are associated with improved developmental outcomes. Early intervention before age three may facilitate transitions toward Balanced or RecAdv profiles, supporting more favorable language development and long-term outcomes.", "url": "https://doi.org/10.64898/2026.06.02.26354680", "doi": "10.64898/2026.06.02.26354680", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.02.26354680", "sources": [ "medRxiv" ] }, { "id": "medRxiv-646976657267696e67207072652d", "title": "Diverging Pre-Pandemic Mortality Trends: Age-Specific and Cause-Specific Patterns Across High-Income Countries", "authors": "Perez-Reche, F.; Summers, J.; Jones, G. T.; Macfarlane, G. J.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "BackgroundMortality rates have declined across most high-income countries for decades, but recent evidence suggests a slowdown in improvements or a shift to increasing mortality, particularly among working-age populations. The international distribution and drivers of these trends remain incompletely understood. MethodsMortality trends during 2012-2019 were analysed using all-cause and cause-specific data from 30 countries. Trends were estimated via linear regression. K-means clustering with Dynamic Time Warping identified countries and ICD-10 chapters with similar temporal trajectories. ResultsTrends varied substantially by nation. While Japan, Switzerland, and the Republic of Korea maintained consistent declines in all-cause mortality rates, increases were concentrated in the United States, Canada, and the United Kingdom, most prominently in persons aged 30-59 years. However, cause-specific analysis showed that rising mortality was not confined to these countries: most countries exhibited increases in at least one ICD-10 chapter, with several European countries showing increases across multiple chapters. Across countries, a small set of causes recurred among increasing trends, including external causes (self-harm, drug poisoning) at younger ages and chronic conditions (cardiovascular and liver diseases, specific cancers) in mid-life. Notably, ill-defined causes of death consistently appeared among the increasing causes across countries and age groups. ConclusionsMortality increases in the 2010s were geographically more widespread than previously recognized. The recurrent rise in mortality from ill-defined causes suggests that an important component of mortality change remains poorly characterized. These findings indicate that stalled health progress is a systemic challenge across many high-income societies. Key MessagesO_LIThis study investigated the distribution and drivers of all-cause and cause-specific mortality trends within 30 countries between 2012 and 2019. C_LIO_LIWhile all-cause mortality increases were most acute in the United Kingdom and North America, cause-specific increases were widespread, with several continental European countries showing rises in multiple causes, including injuries, chronic diseases, and ill-defined conditions. C_LIO_LIThe widespread rise of these diverse mortality drivers, including poorly understood \"ill-defined\" causes, indicates that stalled health progress is a systemic challenge requiring a unified public health response across high-income societies. C_LI", "url": "https://doi.org/10.64898/2026.06.01.26354619", "doi": "10.64898/2026.06.01.26354619", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.26354619", "sources": [ "medRxiv" ] }, { "id": "medRxiv-70726576616c656e636520616e64", "title": "Prevalence and Clinical Determinants of Cognitive Impairment in Diverse Patients with Parkinson's Disease", "authors": "Zirra, A.; Dey, K. C.; Camboe, E.; Bhadra, E.; Laban, R.; Huxford, B.; Hussain-Ali, S.; Simonet, C. C.; Budu, C.; Gallagher, D. A.; Waters, S.; Azoidou, V.; Boyle, T.; Lees, A. J.; Perinan, M. T.; Marshall, C. R.; Noyce, A. J.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "ImportanceThe real-world prevalence and the clinical determinants associated with cognitive impairment in diverse patients with Parkinson disease (PD) have been understudied. ObjectiveTo determine the prevalence of cognitive impairment in a diverse PD cohort and explore associations with vascular, motor, and nonmotor factors. Design, setting and participantsCase-only analysis of diverse patients with PD recruited to the East London Parkinson disease project (July 2022 to July 2025) at the Royal London Hospital, a tertiary referral center. Of 237 patients with cognitive status defined by expert, multi-disciplinary, clinical consensus, 223 remained after excluding atypical or secondary parkinsonism, other dementias, and study withdrawal. ExposuresObservational study (no experimental intervention); exposures included vascular risk factors, motor and nonmotor clinical features. Main Outcome(s) and Measure(s)The main outcome was cognitive impairment (PDCI), defined as mild cognitive impairment (PDMCI) or dementia (PDD) by expert clinical consensus based on clinical, imaging, and cognitive screening. ResultsAmong 223 participants with a median disease duration of 4.0 (1.0-9.0) years, 112 (50.2%) had PDCI, including 62 (27.8%) with PDD and 50 (22.4%) with PDMCI. South Asian ethnicity was associated with PDCI in univariate analysis (OR, 2.30; 95% CI, 1.32-4.00, P = .003) and the association strengthened after adjusting for age, gender, years of education, disease duration and depression scores (OR, 3.60; 95% CI, 1.68-7.69, P < .001). PDCI was associated with increased odds of smoking (OR, 3.62; 95% CI, 1.56-8.41, P = .003) in the adjusted model. Increased odds were also associated with motor severity (Movement Disorders Society Unified Parkinson Disease Rating Scale Part III; OR per point increase 1.07; 95% CI, 1.04-1.10; P < .001), and daytime somnolence score (Epworth Sleepiness Scale; OR per point increase, 1.08; 95% CI, 1.01-1.16; P = .03). Conclusions and RelevanceIn this multi-ethnic study of PD using gold-standard expert multidisciplinary consensus, cognitive impairment was common and more prevalent among South Asian individuals. Smoking, greater motor severity, and higher daytime somnolence were associated with increased odds of cognitive impairment.", "url": "https://doi.org/10.64898/2026.06.02.26354673", "doi": "10.64898/2026.06.02.26354673", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.02.26354673", "sources": [ "medRxiv" ] }, { "id": "medRxiv-61646465642076616c7565206f66", "title": "Added Value of Software-Assisted Analysis in FDG-PET for Neurodegenerative Disease Diagnosis: A Systematic Review and Meta-Analysis", "authors": "Yoon, H.-J.; Lee, Y.; Bang, J.-I.; Kang, S. Y.; Kim, J.-Y.; Choi, M.; Pak, K.", "source": "medRxiv", "field": "Biomedicine", "date": "2026-06-03", "abstract": "BackgroundIn clinical practice, 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) evaluation of neurodegenerative diseases relies primarily on visual interpretation, which is inherently subjective. Although current international guidelines recommend incorporating quantitative tools to support visual reading, the magnitude of the incremental diagnostic benefit and the clinical contexts in which it is most pronounced have not been formally synthesized in a systematic meta-analytic framework. MethodsFollowing the Preferred Reporting Items for Systematic reviews and Meta-Analyses for Diagnostic Test Accuracy (PRISMA-DTA) guidelines, we searched PubMed, EMBASE, Cochrane Library, and KoreaMed from inception to August 2025 for studies comparing visual-only versus visual-plus-quantitative FDG-PET interpretation within identical patient cohorts. Pooled sensitivity and specificity were estimated using random-effects models. Relative diagnostic performance was summarized as odds ratios (ORs), obtained by exponentiation posterior contrasts between visual analysis combined with quantitative analysis, and visual analysis. Subgroup analyses were conducted based on the clinical experience of the readers. ResultsTen studies met the inclusion criteria. In the overall analysis (k = 9), visual analysis alone yielded a pooled sensitivity of 0.85 (95% Confidence interval: 0.77-0.91) and specificity of 0.78 (0.63-0.88), versus a sensitivity of 0.87 (0.82-0.91) and specificity of 0.88 (0.74-0.95) for the combined approach. The most pronounced gain was observed in differentiating Alzheimers disease (AD) from healthy controls, with specificity increasing from 0.69 to 0.94 (Bayesian OR 4.29 (95% Credible interval: 1.87-10.84)). Quantitative augmentation conferred a larger sensitivity gain among beginner readers (increasing from 0.75 to 0.87; Bayesian OR 2.39 [1.33-4.32]) than among expert readers, narrowing the performance gap between experience levels. ConclusionAdding quantitative analysis to visual FDG-PET interpretation yields modest overall improvements in diagnostic accuracy, with the largest gains observed in distinguishing AD from cognitively normal individuals and among less experienced readers. These findings are consistent with current international guidelines that position quantitative assessment as a complementary aid to visual interpretation rather than a replacement, with particular utility for less experienced practitioners and for specific differential-diagnostic scenarios.", "url": "https://doi.org/10.64898/2026.06.01.26354659", "doi": "10.64898/2026.06.01.26354659", "keywords": [ "medicine", "preprint" ], "citations": [], "sourceId": "10.64898/2026.06.01.26354659", "sources": [ "medRxiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323531", "title": "网络首发 --> 试论次要剪接体snRNA是中西医基础研究难题突破口", "authors": "邱忠鹏, 刘亮", "source": "ChinaXiv", "field": "生物学", "date": "2026-06-02", "abstract": "【摘要】背景 关于次要剪接体snRNA、含U12型内含子基因表达，有许多实验异常发现至今机制不明，困扰学术界多年没有突破。目的 系统检索研究次要剪接体snRNA实验论文，提出并验证假说：在体内环境中，神经元、心肌细胞等的次要剪接体 snRNA 并非自身细胞核转录产生，而是由肾小管上皮细胞以外泌体形式分泌，经体液循环跨细胞供给。为次要剪接体snRNA实验异常发现、重大疾病共病机制、衰老及中医肾气科学内涵提供统一解释。方法 检索 1999–2026 年体内/体外次要剪接体 snRNA 定位、母体补偿、肾脏特异性及衰老相关研究 32 项，建立“异常发现”证据链。预实验：以 HK-2 人肾小管上皮细胞为模型，超速离心分离外泌体，qPCR 双内参法定量 U11、U12、U4atac、U6atac snRNA 丰度。 结果 文献整合显示体内环境中细胞的次要剪接体snRNA可能来自肾小管上皮细胞外泌体而非自身核内转录产生；预实验：HK-2 外泌体中可检出 U11、U12、U4atac，其中 U12 相对丰度最高，U6atac 因半衰期极短几乎未检出。 局限 尚未完成体内示踪实验证明肾脏来源次要剪接体snRNA 外泌体的靶器官摄取、肾小管特异性 snRNA 敲除动物模型验证远端组织表型、次要剪接体外泌体 snRNA 功能性剪接重建实验。结论 综合次要剪接体snRNA实验全球意外发现、演化生物学的广谱抗病毒逻辑、初步实验证据等，说明“肾小管上皮细胞外泌体—次要剪接体 snRNA”轴可能是维持全身 U12 型内含子基因稳态的关键跨细胞供给通路。", "url": "https://www.chinaxiv.org/abs/202512.00258", "doi": "10.12074/202512.00258", "keywords": [ "次要剪接体snRNA", "U12型内含子", "肾小管上皮细胞", "外泌体", "肾气", "分子生物学" ], "citations": [ "ChinaXiv:202512.00258", "CSTR:.cn", "https://www.chinaxiv.org/abs/202512.00258v3", "https://www.chinaxiv.org/abs/202512.00258v2", "https://www.chinaxiv.org/abs/202512.00258v1" ], "sourceId": "ChinaXiv:202512.00258", "chinaXiv": { "canonicalId": "ChinaXiv:202512.00258", "versionId": "ChinaXiv:202512.00258", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=ad14d4b4887f4ee5b6bc2908ec8228e2&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202512.00258v3", "https://www.chinaxiv.org/abs/202512.00258v2", "https://www.chinaxiv.org/abs/202512.00258v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 组态相互作用壳模型及奇特核性质研究进展", "authors": "张润泽, 刘梦兰, 袁岑溪", "source": "ChinaXiv", "field": "核科学技术", "date": "2026-06-02", "abstract": "随着核物理实验向远离稳定线区域的拓展，奇特核展现出的壳层演化、集团发射等现象，对微观核结构理论提出了挑战。组态相互作用壳模型（CISM）近年来在解释这些极端条件下的物理机制方面发挥了重要作用。本文介绍了组态相互作用壳模型的理论框架，探讨了组态相互作用壳模型在原子核奇特性质研究上的进展，包括跨壳激发与镜像对称性破缺、多质子结团发射、同核异能态、新核素与集团发射等。文章也总结了在构建跨核区统一有效哈密顿量方面的尝试，并针对核数据关键需求，回顾了基于组态相互作用壳模型的微观能级密度计算方法的应用。", "url": "https://www.chinaxiv.org/abs/202604.00124", "doi": "10.12074/202604.00124", "keywords": [ "组态相互作用壳模型", "核结构", "有效哈密顿量", "跨壳激发", "统一有效核力", "辐射物理与技术" ], "citations": [ "ChinaXiv:202604.00124", "CSTR:.cn", "https://www.chinaxiv.org/abs/202604.00124v2" ], "sourceId": "ChinaXiv:202604.00124", "chinaXiv": { "canonicalId": "ChinaXiv:202604.00124", "versionId": "ChinaXiv:202604.00124", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=0565a7909ed440b983b541646442e9e8&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202604.00124v2" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> Geometric Emergence and Scalar Modes in Vacuum Scalar-Field Gravity", "authors": "Li Xiaoyun", "source": "ChinaXiv", "field": "物理学", "date": "2026-05-28", "abstract": "We present a gravitational framework rooted in a cosmic vacuum scalar field \\(\\phi\\), where the energy relation \\(E = m\\phi\\) and the field equation \\(\\square(\\phi^{2}) = 0\\) define the dynamics. In static spherically symmetric configurations, the Schwarzschild metric emerges geometrically, recovering the classical tests of general relativity. For rotating sources, the non-commutativity of Lorentz transformations along different directions naturally incorporates angular momentum, yielding the Kerr metric in the weak-field limit and reproducing frame-dragging effects relevant to astrophysical black holes such as Sgr A* and M87*. Linear perturbations \\(\\delta\\phi\\) propagate as massless waves and source purely transverse breathing modes in gravitational waves without longitudinal components, offering a polarization signature distinct from general relativity and general scalar-tensor theories. In unequal-mass binary systems, these modes may give rise to scalar dipole radiation, providing observational targets for future space-borne detectors (LISA, TianQin, Taiji) and pulsar timing arrays. On cosmological scales, the background field \\(\\phi_{0}(t)\\) evolves consistently with dark energy dynamics, while the coupling of gravity exclusively to spatial gradients of \\(\\phi\\) decouples vacuum energy from gravitational sources, offering a new perspective on the cosmological constant problem. This framework unifies the description of local gravity, rotating compact objects, gravitational-wave polarization, and cosmic expansion, with testable predictions across multiple astrophysical and cosmological windows.", "url": "https://www.chinaxiv.org/abs/202604.00081", "doi": "10.12074/202604.00081", "keywords": [ "vacuum scalar field", "equivalence principle", "Schwarzschild metric", "Kerr metric", "scalar gravitational waves", "breathing mode", "geometric emergence", "cosmological constant problem", "地球物理学、天文学和天体物理学" ], "citations": [ "ChinaXiv:202604.00081", "CSTR:.cn", "https://www.chinaxiv.org/abs/202604.00081v6", "https://www.chinaxiv.org/abs/202604.00081v5", "https://www.chinaxiv.org/abs/202604.00081v1" ], "sourceId": "ChinaXiv:202604.00081", "chinaXiv": { "canonicalId": "ChinaXiv:202604.00081", "versionId": "ChinaXiv:202604.00081", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=4f9b99ae19dc4d8db957af4e5af461b8&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202604.00081v6", "https://www.chinaxiv.org/abs/202604.00081v5", "https://www.chinaxiv.org/abs/202604.00081v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> A Time Scaling Theory for Multi-Layer Electronic Systems", "authors": "Tingbo He", "source": "ChinaXiv", "field": "电子与通信技术", "date": "2026-05-25", "abstract": "For six decades, Moore's geometric scaling drove progress in semiconductors. That industry compact no longer holds: returns from pure dimensional shrinking have flattened, leading-edge design budgets exceed one billion dollars per chip, and cost-per-transistor at the most advanced nodes is no longer falling. This perspective argues for a successor scaling principle — τ scaling —that adopts time itself, rather than transistor area, as the primary metric of progress, applying a single characteristic time constant τ as the unifying optimization target across twelve orders of magnitude, from a switching transistor to a data-center workload. Two production-scale demonstrations are presented. On a mobile SoC, LogicFolding — a methodology that partitions digital, analog, and memory circuits across vertically stacked active tiers — delivers a 55% step-wise increase in transistor density and a 41% power-efficiency gain at a fixed device node. On AI systems, a co-designed stack comprising the memory-semantic Unified Bus fabric, near-packaged Hi-ONE optical I/O, and edge-to-surface 3D Folding projects more than 100× growth in hardware integration by 2035.The deeper claim is methodological: τ scaling is the first scaling principle since Dennard to establish a shared optimization target across the entire computing stack.", "url": "https://www.chinaxiv.org/abs/202605.00224", "doi": "10.12074/202605.00224", "keywords": [ "Time Scaling", "τ scaling", "LogicFolding", "Semiconductor", "Electronic systems", "New semiconductor path", "半导体技术" ], "citations": [ "ChinaXiv:202605.00224", "CSTR:.cn", "https://www.chinaxiv.org/abs/202605.00224v1" ], "sourceId": "ChinaXiv:202605.00224", "chinaXiv": { "canonicalId": "ChinaXiv:202605.00224", "versionId": "ChinaXiv:202605.00224", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=9acd993240d5482ea1ee6fdb470c095f&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202605.00224v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 甲醇诱导竞争配位构建配体缺陷型乙二醇氧钒用于高性能水系锌离子电池", "authors": "吴萌, 李兴华", "source": "ChinaXiv", "field": "物理学", "date": "2026-05-25", "abstract": "水系锌离子电池（AZIBs）正极材料乙二醇氧钒（VEG）具有稳定的一维链状有机-无机杂化结构，但其致密的配体网络严重限制了Zn 2+ 的快速传输。针对此问题，本文提出一种甲醇诱导的竞争配位策略：利用甲醇（MeOH）与乙二醇（EG）的竞争配位，以单齿配体MeOH部分取代双齿配体EG，并终止其桥连作用，从而成功构建具有配体缺陷的VEG-Me材料。电化学动力学分析表明，与VEG相比，具有配体缺陷的VEG-Me其Zn 2+ 扩散系数提升了一个数量级（高达1.97×10- 11 ~2.32×10 -10 cm 2 s -1 ），电荷转移活化能显著降低24%（仅为18.469 kJ mol -1 ），表明配体缺陷的形成促进了Zn 2+ 储能过程中的电荷转移能力。以VEG-Me为正极，经集流体优化后电极表现出优异的倍率性能（0.1 A g -1 下容量达370.9 mAh g -1 ，5 A g -1 时达225.8 mAh g -1 ）以及超高的循环稳定性（5 A g -1 循环500次后容量保持率达96.45%）。本工作为通过分子级别配体工程设计高性能有机-无机杂化储能材料提供了新思路。", "url": "https://www.chinaxiv.org/abs/202605.00226", "doi": "10.12074/202605.00226", "keywords": [ "水系锌离子电池", "正极材料", "有机无机杂化氧化钒", "乙二醇氧钒", "配体缺陷", "凝聚态:电子结构、电、磁和光学性质" ], "citations": [ "ChinaXiv:202605.00226", "CSTR:.cn", "https://www.chinaxiv.org/abs/202605.00226v1" ], "sourceId": "ChinaXiv:202605.00226", "chinaXiv": { "canonicalId": "ChinaXiv:202605.00226", "versionId": "ChinaXiv:202605.00226", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=28f3e66700ba496dafa8737dad88185d&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202605.00226v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 新疆地质旅游空间协同区划研究 后印本", "authors": "白洋, 赵平, 李永峰, 陈明珠, 孙艺玥", "source": "ChinaXiv", "field": "地球科学", "date": "2026-05-25", "abstract": "搜集2024年新疆地质遗迹、A级景区与基础设施POI等县域数据，运用空间分析技术和数理统计模型，基于共生理论分析要素协同发展的空间分布特征与共生协调等级，以“地质+旅游”共生发展为主导、基础设施配套服务为支撑，进行空间协同区划。结果表明：（1）各要素均为显著空间集聚分布，空间集聚程度排序为整体基础设施>A级景区>地质遗迹。（2）地质遗迹、A级景区和整体基础设施空间密度分别呈现“一带单核单极”“双极三核”和“单极单核”的分布特征，标准差椭圆反映各要素空间分布方向大体一致，重心均在和静县境内。（3）地质遗迹对A级景区、整体基础设施存在吸引倾向，全局空间协同水平较低。地质遗迹与A级景区、基础设施局部空间协同水平分别呈现“西高东低、南强北弱”的分布态势。（4）全疆共生协调等级呈现“橄榄球型”等级结构，中高级共生协调占据主导，北疆以中高级共生协调为主，南疆以中级共生协调为主。（5）基于分析结果，提炼出5种新疆地质旅游空间协同区划,并提出相应开发模式与优化路径。", "url": "https://www.chinaxiv.org/abs/202605.00229", "doi": "10.12074/202605.00229", "keywords": [ "新疆", "地质遗迹", "A 级景区", "基础设施", "空间协同区划", "共生理论", "地理学" ], "citations": [ "ChinaXiv:202605.00229", "CSTR:.cn", "https://www.chinaxiv.org/abs/202605.00229v1" ], "sourceId": "ChinaXiv:202605.00229", "chinaXiv": { "canonicalId": "ChinaXiv:202605.00229", "versionId": "ChinaXiv:202605.00229", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=f5fdb9ced7644b88babe7bd5a58e7c25&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202605.00229v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 开放科学实践的草根路径：以心理与脑科学为例", "authors": "岳磊, 左西年, 胡传鹏", "source": "ChinaXiv", "field": "心理学", "date": "2026-05-25", "abstract": "开放科学能实现科学资源的有效共享和充分利用，重塑科研实践与文化，但其发展仍处于初生阶段。文章以心理与脑科学为例，阐述该领域从增强本研究的可信度和科学性出发，自发地开启了开放科学的草根运动，推动本领域科研全过程的开放科学实践，并引领跨学科的开放科学行动和文化塑造。文章还分析了心理与脑科学开放科学实践蓬勃发展的原因，为我国进一步推动开放科学发展提供建议。", "url": "https://www.chinaxiv.org/abs/202605.00198", "doi": "10.12074/202605.00198", "keywords": [ "开放科学", "草根路径", "心理科学", "脑科学", "心理学史" ], "citations": [ "ChinaXiv:202605.00198", "CSTR:.cn", "https://www.chinaxiv.org/abs/202605.00198v2", "https://www.chinaxiv.org/abs/202605.00198v1" ], "sourceId": "ChinaXiv:202605.00198", "chinaXiv": { "canonicalId": "ChinaXiv:202605.00198", "versionId": "ChinaXiv:202605.00198", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=680772229cdb4d649c8769219cbec8e6&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202605.00198v2", "https://www.chinaxiv.org/abs/202605.00198v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 耦合岩石力学与渗流能力的地层可压性机理及工程启示", "authors": "齐亚林", "source": "ChinaXiv", "field": "地球科学", "date": "2026-05-20", "abstract": "水力压裂是非常规油气高效开发的核心技术，地层可压性评价是压裂方案优化与产能释放的关键前提。当前行业普遍存在将“岩石易开裂”等同于“可压性好”的认知误区，多以脆性矿物含量作为单一评价指标，忽视了多因素耦合效应。以砂岩与泥岩为典型对象，基于岩石力学与储层渗流理论，系统分析抗拉强度与固有断裂韧性（KIC）的内涵、影响因素及辩证关系，重点引入流体渗流-裂缝尖端耗能耦合机制，揭示裂缝起裂与扩展阶段的差异化力学响应，探讨岩石力学特性、脆性矿物、储层渗流能力与可压性的耦合作用机理。在此基础上，将分析尺度从单裂缝延伸拓展至多裂缝缝网，引入最小能量原理控制的方位判据，建立裂缝转向与分叉的力学条件，并揭示应力阴影的双面工程调控作用。研究表明：地层可压性是岩石力学与渗流能力协同耦合的结果，非单一指标独立控制。抗拉强度控制起裂阈值，固有断裂韧性控制扩展阻力，二者整体呈正相关但功能本质不同。渗流能力是可压性评价的“第一性”参数。脆性矿物通过正向（改善渗流）与负向（增大模量）双重效应调控可压性，净贡献由胶结类型主导。裂缝延伸阶段，流体通过改变断裂过程区（FPZ）的能量耗散特征，主导视断裂韧性（KIC,app）：砂岩因渗流能力强，流体可有效进入FPZ，视断裂韧性低、易延伸；泥岩因渗流能力弱，流体受阻，视断裂韧性高、难延伸。裂缝能否形成复杂缝网，取决于渗流能力门槛、地应力与抗拉强度之和的方位竞争（总阻力函数 σ(θ)+St(θ) 的极值分布）、天然裂缝发育程度以及应力阴影调控的四重耦合。当总阻力函数在某一主应力主轴方向取唯一最小值时，裂缝被地应力场锁定，仅单向平直延伸（“可压开但不可控网”）；当存在多个方位极小值且差值较小时，裂缝具备转向分叉的力学条件。最优“工程甜点”储层特征为“渗流能力优异 + 弱胶结 + 脆性矿物含量适中”。研究结果为可压性综合评价提供了新理论视角与工程参考。", "url": "https://www.chinaxiv.org/abs/202604.00218", "doi": "10.12074/202604.00218", "keywords": [ "地层可压性", "抗拉强度", "断裂韧性", "脆性矿物", "渗流能力", "耦合机理" ], "citations": [ "ChinaXiv:202604.00218", "CSTR:.cn", "https://www.chinaxiv.org/abs/202604.00218v2" ], "sourceId": "ChinaXiv:202604.00218", "chinaXiv": { "canonicalId": "ChinaXiv:202604.00218", "versionId": "ChinaXiv:202604.00218", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=1cff29a147674e478591c408647ca6b0&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202604.00218v2" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323530", "title": "网络首发 --> Can a particle behave as a wave in self-reference frame ?", "authors": "Qiankai Yao", "source": "ChinaXiv", "field": "物理学", "date": "2026-05-18", "abstract": "As to matter wave, an interesting question is whether a particle can behave as a wave in the frame tied to itself. If the answer is negative, it is possible to establish a self-reference frame to cancel the particle’s waveform, and even develop a metric field equation to describe wave-particle duality as a geodesic effect. Meanwhile, it also shows that in addition to on-site verification, another efficacy of physical measurement is to systematically reset the quantum geodesic curve of measured object. This retroactive reset not only prunes a randomly selectable history into a causal course with specific trend, but also makes the verified a historical inevitability dominated by geodesic geometry. The procedure adopted here will provide a conceptually different explanation for irreversible quantum collapse and entanglement.", "url": "https://www.chinaxiv.org/abs/202507.00100", "doi": "10.12074/202507.00100", "keywords": [ "Self-reference frame", "Uncertainty principle", "Complementarity principle", "Quantum geometrization", "普通物理:统计和量子力学,量子信息等" ], "citations": [ "ChinaXiv:202507.00100", "CSTR:.cn", "https://www.chinaxiv.org/abs/202507.00100v2", "https://www.chinaxiv.org/abs/202507.00100v1" ], "sourceId": "ChinaXiv:202507.00100", "chinaXiv": { "canonicalId": "ChinaXiv:202507.00100", "versionId": "ChinaXiv:202507.00100", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=53805b70553c45859aec33f727c63a1b&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202507.00100v2", "https://www.chinaxiv.org/abs/202507.00100v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 基于贝叶斯模型平均的元分析：原理与实现", "authors": "任子伟, 刘铮, 胡传鹏", "source": "ChinaXiv", "field": "心理学", "date": "2026-05-17", "abstract": "元分析作为一种综合已有研究成果的重要统计方法，在量化研究中广泛应用。然而，研究者在分析过程中常面临模型选择的困境：在处理研究间异质性时，需在固定效应与随机效应模型之间做出选择；在应对潜在发表偏倚时，又需要从多种校正模型中选定一种。目前，这些模型选择仍缺乏统一标准。贝叶斯统计框架下的贝叶斯模型平均(Bayesian Model Averaging, BMA)为解决这些问题提供了新的思路：它将不同统计模型纳入同一模型空间，量化各模型获得数据支持的程度，并据此对效应量进行加权，从而规避单一模型选择带来的不确定性。基于BMA的元分析能同时检验三个关键假设(效应是否存在、异质性是否存在以及发表偏倚是否存在)，并以模型平均的方式实现对效应量的稳健估计。该方法可通过开源软件 JASP 或 R 语言实现，为研究者实施元分析提供了新选择。", "url": "https://www.chinaxiv.org/abs/202605.00116", "doi": "10.12074/202605.00116", "keywords": [ "贝叶斯模型平均", "元分析", "模型不确定性", "发表偏倚", "稳健贝叶斯元分析", "认知心理学" ], "citations": [ "ChinaXiv:202605.00116", "CSTR:.cn", "https://www.chinaxiv.org/abs/202605.00116v1" ], "sourceId": "ChinaXiv:202605.00116", "chinaXiv": { "canonicalId": "ChinaXiv:202605.00116", "versionId": "ChinaXiv:202605.00116", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=11f91b81d98543418b14998ba1c2f20c&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202605.00116v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> SPSS-MCP：基于 Claude Code 的心理统计自动化系统", "authors": "薛茎申, 朱廷劭", "source": "ChinaXiv", "field": "心理学", "date": "2026-04-10", "abstract": "本文介绍了一种将Claude Code接入 IBM SPSS Statistics深度集成的方法，通过开发基于 Model Context Protocol（MCP）的 SPSS 服务器（SPSS-MCP），使 Claude Code 能够直接调用 SPSS 执行统计分析。系统基于 SPSS XD API 构建统一执行引擎，要求 Windows 环境下已安装 IBM SPSS Statistics，所有统计分析均通过该引擎调用 SPSS 后端完成。服务器共提供 36 个工具，涵盖基础统计、高级回归、多层模型、生存分析、多元分析、聚类分析和信度分析等心理学研究中的常用统计方法。本文详细说明了系统架构、核心技术实现原理，并针对心理学研究人员提出了最佳实践建议，旨在帮助研究者借助 AI 辅助显著提升统计分析的效率与可及性。", "url": "https://www.chinaxiv.org/abs/202604.00159", "doi": "10.12074/202604.00159", "keywords": [ "模型上下文协议", "IBM SPSS Statistics", "大语言模型", "统计分析自动化", "应用心理学" ], "citations": [ "ChinaXiv:202604.00159", "CSTR:.cn", "https://www.chinaxiv.org/abs/202604.00159v1" ], "sourceId": "ChinaXiv:202604.00159", "chinaXiv": { "canonicalId": "ChinaXiv:202604.00159", "versionId": "ChinaXiv:202604.00159", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=e8b22b1a5b354e80a81bc69f8a0d8bfa&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202604.00159v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 漂移扩散模型的理论基础及其合理使用的路径", "authors": "王琪惠, 任子伟, 胡传鹏, 王益文", "source": "ChinaXiv", "field": "心理学", "date": "2026-03-24", "abstract": "漂移扩散模型被广泛应用于不同领域的反应时分析。然而，当前文献缺少对 DDM 的数学模型、参数估计算法和工具及如何合理使用的系统阐述。本文首先回顾了 DDM 的数学基础——首次通过时间函数，强调 DDM 从统计模型到认知模型这一逻辑飞跃中的关键模型预设，简述 DDM 参数估计的算法及其软件实现；在此基础上强调模型预设对实验任务设计与参数解读的约束，并指出两种可能使用 DDM 的路径：严格使用标准 DDM 或者对其进行拓展。", "url": "https://www.chinaxiv.org/abs/202601.00206", "doi": "10.12074/202601.00206", "keywords": [ "决策", "证据积累模型", "漂移扩散模型", "认知心理学" ], "citations": [ "ChinaXiv:202601.00206", "CSTR:.cn", "https://www.chinaxiv.org/abs/202601.00206v4", "https://www.chinaxiv.org/abs/202601.00206v3", "https://www.chinaxiv.org/abs/202601.00206v2", "https://www.chinaxiv.org/abs/202601.00206v1" ], "sourceId": "ChinaXiv:202601.00206", "chinaXiv": { "canonicalId": "ChinaXiv:202601.00206", "versionId": "ChinaXiv:202601.00206", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=18ec125622f44326880785f8131f8e55&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202601.00206v4", "https://www.chinaxiv.org/abs/202601.00206v3", "https://www.chinaxiv.org/abs/202601.00206v2", "https://www.chinaxiv.org/abs/202601.00206v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323630", "title": "网络首发 --> 小学生父母自我关怀对消极情绪的影响及干预研究", "authors": "孙燕, 赵媚", "source": "ChinaXiv", "field": "心理学", "date": "2026-03-24", "abstract": "研究目的：本研究对小学生父母进行为期一周的整合式催眠增强冥想结合自我关怀干预，研究该干预方法对自我关怀、反刍思维、教养压力、消极情绪的影响及机制。 研究结果：干预显著减少了消极情绪，缓解了自我关怀中的自我批评、孤离感、过度沉浸维度，降低了反刍思维中的反省深思维度，并且改善了教养压力中的困难儿童维度；自我关怀变化量与反刍思维变化量、教养压力变化量、消极情绪变化量为显著负相关，反刍思维变化量、教养压力变化量、消极情绪变化量为显著正相关；干预在自我关怀对反刍思维的影响中起到了显著的调节作用，对自我关怀、反刍思维、教养压力、消极情绪4个变量的整体调节作用显著。 研究结论：短程催眠增强冥想结合自我关怀练习能够有效提高小学生家长的自我关怀水平，减少消极情绪，反刍思维和教养压力可能在其中发挥了中介作用。", "url": "https://www.chinaxiv.org/abs/202603.00132", "doi": "10.12074/202603.00132", "keywords": [ "自我关怀", "反刍思维", "教养压力", "消极情绪", "催眠增强冥想", "心理健康", "应用心理学" ], "citations": [ "ChinaXiv:202603.00132", "CSTR:.cn", "https://www.chinaxiv.org/abs/202603.00132v1" ], "sourceId": "ChinaXiv:202603.00132", "chinaXiv": { "canonicalId": "ChinaXiv:202603.00132", "versionId": "ChinaXiv:202603.00132", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=5d9453ce68b3441ea55fa89b742de173&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202603.00132v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323430", "title": "网络首发 --> 调和级数教学设计", "authors": "刘宏准", "source": "ChinaXiv", "field": "数学", "date": "2026-03-23", "abstract": "调和级数是无穷级数中极具重要性的一类，作为P-级数的关键特例，它是区分P-级数收敛与发散的核心分界点。其英文名称“Harmonic series”与泛音列的英文完全一致，这一命名并非偶然，而是与它的起源有着密切关联。同时，调和级数的发散性结论，还可应用于验证比萨斜塔相关实验结论的科学性。 在《微积分》教学过程中，若能清晰讲解调和级数的相关背景知识与实际应用，不仅能有效激发学生对数学知识的探索兴趣和学习热情，更能帮助学生缓解乃至克服对《微积分》课程的畏难情绪，增强其学习信心。另一方面，这样的教学内容设计，巧妙串联起看似孤立的知识点，生动诠释了“事物是普遍联系”的哲学观点，实现了知识传授与思政教育的有机融合。 有鉴于此，笔者撰写本文，旨在抛砖引玉，期许更多一线教师能够分享自身的成功教学心得与新颖教学发现，携手发力、共同探索，不断完善《微积分》课程的思政教学素材，不断提升课程教学质量与育人实效。", "url": "https://www.chinaxiv.org/abs/202409.00221", "doi": "10.12074/202409.00221", "keywords": [ "调和级数", "里拉斜塔", "思政教学", "微积分", "数学（综合）" ], "citations": [ "ChinaXiv:202409.00221", "CSTR:.cn", "https://www.chinaxiv.org/abs/202409.00221v3", "https://www.chinaxiv.org/abs/202409.00221v2", "https://www.chinaxiv.org/abs/202409.00221v1" ], "sourceId": "ChinaXiv:202409.00221", "chinaXiv": { "canonicalId": "ChinaXiv:202409.00221", "versionId": "ChinaXiv:202409.00221", "pdfUrl": 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G, Kpetikou G, Yédomonhan H, Hedderson T, Adomou A", "source": "PubMed", "field": "Interdisciplinary", "date": "2026 Jun 1", "abstract": "", "url": "https://pubmed.ncbi.nlm.nih.gov/42304201/", "doi": "", "keywords": [ "medicine", "PubMed" ], "citations": [], "sourceId": "42304201", "sources": [ "PubMed" ] }, { "id": "PubMed-7469727a6570617469646520666f", "title": "Tirzepatide for Excess Weight in Adults With Type 1 Diabetes Using MiniMed 780G.", "authors": "De Fano M, Tortoriello R, Rucco S, Corio S, Manco M, Guerrini E, Porcellati F", "source": "PubMed", "field": "Interdisciplinary", "date": "2026 Jun 1", "abstract": "", "url": "https://pubmed.ncbi.nlm.nih.gov/42304199/", "doi": "", "keywords": [ "medicine", "PubMed" ], "citations": [], "sourceId": "42304199", "sources": [ "PubMed" ] }, { "id": "PubMed-70756c6d6f6e61727920746f7869", "title": "Pulmonary toxicity of micro- and nano polyethylene particles following intratracheal instillation in rats.", "authors": "Han HY, Hwangbo S, Park 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"https://pubmed.ncbi.nlm.nih.gov/42304189/", "doi": "", "keywords": [ "medicine", "PubMed" ], "citations": [], "sourceId": "42304189", "sources": [ "PubMed" ] }, { "id": "PubMed-696e697469616c206f7574636f6d", "title": "Initial Outcomes Following Treatment With Topical Corticosteroids or Topical Calcineurin Inhibitors in Cats With Eosinophilic Keratitis.", "authors": "Pletcher JS, Lassaline ME, Wu T, Holt E", "source": "PubMed", "field": "Interdisciplinary", "date": "2026 Jul", "abstract": "", "url": "https://pubmed.ncbi.nlm.nih.gov/42304203/", "doi": "", "keywords": [ "medicine", "PubMed" ], "citations": [], "sourceId": "42304203", "sources": [ "PubMed" ] }, { "id": "chinaxiv-6368696e617869763a3230323530", "title": "网络首发 --> 非重整化奇点消解与黑洞阴影验证", "authors": "黄海", "source": "ChinaXiv", "field": "天文学", "date": "2025-11-28", "abstract": "本文提出一种基于量子拓扑结构的非微扰量子引力新框架，通过引入“量子涡旋”表征微观粒子统计平均的拓扑序，并嵌入AdS/CFT全息对偶，在无需重整化的条件下消除黑洞奇点。理论推导表明：量子涡旋场产生的引力势 在临界半径内形成斥力屏障，动力学禁止物质抵达奇点（r=0），彻底避免曲率发散。构建的黄氏度规（带量子引力修正的史瓦西度规）可无自由参数预测黑洞阴影角直径，无需观测后拟合克尔黑洞自旋。 观测验证表明：Sgr A*的理论阴影角直径为53.3μas，与EHT实测（51.8±2.3μas）高度吻合；M87*的理论阴影角直径为46.2μas，落在EHT实测（42±3μas）的合理误差范围内，从源头上解决了克尔黑洞模型在解释M87*阴影时的内在矛盾（黑洞最大自旋的理论视角与实际视角不符）。 本理论首次实现量子引力对奇点消除、信息守恒及黑洞阴影的联合解释，为探索时空量子结构提供首个可检验量子引力框架。", "url": "https://www.chinaxiv.org/abs/202507.00323", "doi": "10.12074/202507.00323", "keywords": [ "量子引力", "广义相对论", "奇点", "黑洞", "度规", "量子涡旋", "事件视界望远镜", "AdS/CFT对偶", "银河系", "M87星系", "仙女座星系", "凤凰座星系" ], "citations": [ "ChinaXiv:202507.00323", "CSTR:.cn", "https://www.chinaxiv.org/abs/202507.00323v5", "https://www.chinaxiv.org/abs/202507.00323v4", "https://www.chinaxiv.org/abs/202507.00323v3", "https://www.chinaxiv.org/abs/202507.00323v2", "https://www.chinaxiv.org/abs/202507.00323v1" ], "sourceId": "ChinaXiv:202507.00323", "chinaXiv": { "canonicalId": "ChinaXiv:202507.00323", "versionId": "ChinaXiv:202507.00323", "pdfUrl": 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－0.21），二者均为中等水平效应量；中庸思维与心理弹性、工作满意度、工作幸福感的相关高于其与生活满意度的相关；中庸思维和幸福感、安适感、积极情绪的相关与其和生活满意度的相关无显著差异。使用中庸信念—价值量表、中庸意见表达量表以及中庸价值取向量表测得的效应量彼此差异较小，且与中庸实践自评量表测得的效应量差异显著。结合元分析的结果，对中庸思维的理论内涵、测量方式，及其与心理健康的关系进行了讨论，指出从超越二元对立的“执中致和”视角理解中庸思维与心理健康所具有的理论建构意义。", "url": "https://www.chinaxiv.org/abs/202511.00179", "doi": "10.12074/202511.00179", "keywords": [ "中庸思维", "心理健康", "三水平元分析", "社会心理学" ], "citations": [ "ChinaXiv:202511.00179", "CSTR:.cn", "https://www.chinaxiv.org/abs/202511.00179v1" ], "sourceId": "ChinaXiv:202511.00179", "chinaXiv": { "canonicalId": "ChinaXiv:202511.00179", "versionId": "ChinaXiv:202511.00179", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=6dcf8ec8-6adb-40e1-9c5b-88d81623d856&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202511.00179v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323531", "title": "网络首发 --> 权威性与AI生成内容的信任悖论：基于漂移扩散模型的认知决策机制", "authors": "杨娟, 苏胜, 康春花", "source": "ChinaXiv", "field": "心理学", "date": "2025-11-24", "abstract": "本研究通过实验设计并构建漂移扩散模型探讨了新闻的生成形式与信源权威性对信任决策及其认知机制的影响。结果发现：信任率、反应时与决策过程均受到生成形式与信源权威性的交互影响，相比于非权威机构，人们对来自权威机构的AI生成的新闻的信任率更低，决策反应时更长，且决策过程中的证据累积速度（v）及起始点偏差（z）更低。研究表明权威媒体盲目引入AI技术可能对其公信力造成损害，使其在智能化转型过程中面临信任危机。", "url": "https://www.chinaxiv.org/abs/202511.00174", "doi": "10.12074/202511.00174", "keywords": [ "信源权威性", "信任决策", "AI生成", "新闻", "漂移扩散模型" ], "citations": [ "ChinaXiv:202511.00174", "CSTR:.cn", "https://www.chinaxiv.org/abs/202511.00174v1" ], "sourceId": "ChinaXiv:202511.00174", "chinaXiv": { "canonicalId": "ChinaXiv:202511.00174", "versionId": "ChinaXiv:202511.00174", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=5207d728-aca1-4a48-8ced-bb93654063f0&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202511.00174v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323531", "title": "网络首发 --> 生成式大语言模型赋能心理测量学：优势、挑战与应用", "authors": "田雪涛, 周文杰, 骆方, 乔志宏, 丰怡", "source": "ChinaXiv", "field": "心理学", "date": "2025-10-22", "abstract": "生成式大语言模型(LLMs)是一种在大规模语料库上预训练的人工智能模型，为心理测量学领域带来前所未有的机遇和挑战。本文通过整合人工智能与心理学交叉研究发展脉络，总结LLMs赋能心理测量学的显著优势，定位LLMs在心理学应用中的重要挑战，并提出基于LLMs的心理测量研究发展方向。具体地，LLMs能够基于上下文生成连贯的自然语言文本，具有改变传统测验交互方式的潜力；LLMs突破对超长文本和多模态数据的处理能力，其强大的内容理解能力能够全面获取和分析被试的心理信息；LLMs有助于实现实时分析和个性化反馈，促进从结果评价向过程评价的转变。尽管LLMs的实际应用面临着稳定性、创造性和拓展性等挑战，但在情境判断测验生成、合作式问题解决能力评估、心理健康智慧诊疗和试题质量分析等领域展现出广阔的应用前景和研究价值。", "url": "https://www.chinaxiv.org/abs/202510.00113", "doi": "10.12074/202510.00113", "keywords": [ "生成式大语言模型", "心理测量学", "人工智能", "自动化评估", "交互式测验", "心理测量" ], "citations": [ "ChinaXiv:202510.00113", "CSTR:.cn", "https://www.chinaxiv.org/abs/202510.00113v1" ], "sourceId": "ChinaXiv:202510.00113", "chinaXiv": { "canonicalId": "ChinaXiv:202510.00113", "versionId": "ChinaXiv:202510.00113", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=7d4d5224-f90e-4e24-9767-440b91b8dc89&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202510.00113v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323531", "title": "网络首发 --> 漂移扩散模型基础及其Python分析流程", "authors": "王琪惠, 任子伟, 胡传鹏", "source": "ChinaXiv", "field": "心理学", "date": "2025-10-14", "abstract": "漂移扩散模型（Drift Diffusion Model, DDM）是研究人类二元决策的典型计算模型，该模型假定个体在作出选择前会持续采样并整合与选项相关的证据，当积累的证据量达到预设的决策边界时，决策即被触发并执行。分层漂移扩散模型（Hierarchical Drift Diffusion Model, HDDM）在DDM基础上引入贝叶斯分层建模方法，通过同时建模个体层面和群体层面的参数，实现信息在不同层级间的共享，从而显著提高了参数估计的统计效力。然而，HDDM的合理使用需要研究者具备相应的理论基础与技术能力，包括理解模型的适用条件、实验设计要求以及掌握具体的建模与参数推断方法。为帮助研究者规范应用HDDM，本文提供了一份系统的使用指南。在理论部分，我们从证据积累模型这一源头理论出发，详细介绍DDM的模型预设及其对实验设计的约束条件，帮助研究者判断DDM是否适用于特定的研究问题。在实践部分，我们基于dockerHDDM工具，提供完整的标准化分析工作流。具体包括：Docker环境安装与dockerHDDM部署、数据预处理、模型构建与拟合、模型比较、统计推断及结果报告等标准化流程。最后，我们还提供了在dockerHDDM实际应用中的实用建议。本文旨在构建从DDM理论到实践应用的完整桥梁，促进HDDM在认知研究中的规范使用。", "url": "https://www.chinaxiv.org/abs/202510.00076", "doi": "10.12074/202510.00076", "keywords": [ "DDM:漂移扩散模型:HDDM:认知建模", "认知心理学" ], "citations": [ "ChinaXiv:202510.00076", "CSTR:.cn", "https://www.chinaxiv.org/abs/202510.00076v1" ], "sourceId": "ChinaXiv:202510.00076", "chinaXiv": { "canonicalId": "ChinaXiv:202510.00076", "versionId": "ChinaXiv:202510.00076", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=a1c4efd3-3be5-47f6-ae94-3280bb8fc346&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202510.00076v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323531", "title": "网络首发 --> 心理—地理基底嵌套理论：一个生态、文化与心理的多层级整合框架", "authors": "务凯, 李永鑫", "source": "ChinaXiv", "field": "心理学", "date": "2025-10-13", "abstract": "人类心理活动并非孤立存在，而是深深嵌入地理与生态环境之中。地理基底既设定约束与压力，也提供资源与可能性，而人类在应对过程中逐步形成文化实践与认知模式。心理—地理基底嵌套理论提出“地理基底—微观传导—文化原型”三大逻辑维度，并在操作层面细化为五个层级，揭示了从物理环境到心理认知的因果链条。模型强调具身认知、社会学习、文化工具与认知图式的协同作用，说明宏观生态条件如何转化为文化原型与个体心理倾向，并在反馈循环、历史惯性与外部调节中展现动态演化特征。以水稻理论、美国南方荣誉文化、日本文化心理的生态起源与民族音乐的地理依托等案例，展示了该理论的解释力与跨学科潜能，为理解文化多样性与认知起源提供了新视角。", "url": "https://www.chinaxiv.org/abs/202510.00075", "doi": "10.12074/202510.00075", "keywords": [ "心理—地理基底嵌套理论", "文化图式", "具身认知", "心理学其他学科" ], "citations": [ "ChinaXiv:202510.00075", "CSTR:.cn", "https://www.chinaxiv.org/abs/202510.00075v1" ], "sourceId": "ChinaXiv:202510.00075", "chinaXiv": { "canonicalId": "ChinaXiv:202510.00075", "versionId": "ChinaXiv:202510.00075", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=c72d4991-4716-4eb7-a8bf-6614300ecaaa&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202510.00075v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323430", "title": "网络首发 --> An efficient implementation for solving the all pairs minimax path problem in an undirected dense graph", "authors": "Gangli Liu", "source": "ChinaXiv", "field": "计算机科学", "date": "2025-08-27", "abstract": "We provide an efficient $ O(n^2) $ implementation for solving the all pairs minimax path problem or widest path problem in an undirected dense graph. It is a code implementation of the Algorithm 4 (MMJ distance by Calculation and Copy) in a previous paper. The distance matrix is also called the all points path distance (APPD). We conducted experiments to test the implementation and algorithm, compared it with several other algorithms for solving the APPD matrix. Result shows Algorithm 4 works good for solving the widest path or minimax path APPD matrix. It can drastically improve the efficiency for computing the APPD matrix. There are several theoretical outcomes which claim the APPD matrix can be solved accurately in $ O(n^2) $ . However, they are impractical because there is no code implementation of these algorithms. It seems Algorithm 4 is the first algorithm that has an actual code implementation for solving the APPD matrix of minimax path or widest path problem in $ O(n^2) $, in an undirected dense graph.", "url": "https://www.chinaxiv.org/abs/202407.00106", "doi": "10.12074/202407.00106", "keywords": [ "Minimax path problem", "Longest-leg path distance", "Min-Max-Jump distance", "Widest path problem", "Maximum capacity path problem", "All points path distance", "Minimum spanning tree", "计算机科学的集成理论" ], "citations": [ "ChinaXiv:202407.00106", "CSTR:.cn", "https://www.chinaxiv.org/abs/202407.00106v5", "https://www.chinaxiv.org/abs/202407.00106v4", "https://www.chinaxiv.org/abs/202407.00106v3", "https://www.chinaxiv.org/abs/202407.00106v2", "https://www.chinaxiv.org/abs/202407.00106v1" ], "sourceId": "ChinaXiv:202407.00106", "chinaXiv": { "canonicalId": "ChinaXiv:202407.00106", "versionId": "ChinaXiv:202407.00106", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=067c3ddc-0a36-4108-8929-f1da94308acb&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202407.00106v5", "https://www.chinaxiv.org/abs/202407.00106v4", "https://www.chinaxiv.org/abs/202407.00106v3", "https://www.chinaxiv.org/abs/202407.00106v2", "https://www.chinaxiv.org/abs/202407.00106v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323530", "title": "网络首发 --> 悲伤与亲社会行为关系的三水平元分析", "authors": "范伟, 程颖", "source": "ChinaXiv", "field": "心理学", "date": "2025-07-19", "abstract": "作为人类最基本的情感体验之一，悲伤对亲社会行为的影响机制在学界长期存在争议。传统观点多强调其消极作用，但实证研究结果却存在明显分歧。为厘清这一争议并揭示研究结果不一致的原因，本研究采用随机效应模型，对近50年来41项研究(70个效应量，总样本量为10173人)进行三水平元分析。结果发现，悲伤与亲社会行为之间存在微弱但显著的正相关(r=0.13,95%CI[0.08,0.18])，年龄阶段显著调节该效应，而性别、诱发方式等因素无显著影响；P曲线(p-curve)分析证实了该效应的真实性，排除了出版偏倚或phacking的可能。研究突破了传统对悲伤的负面认知，揭示悲伤情绪蕴含的亲社会转化潜能，为情绪干预提供了新视角。", "url": "https://www.chinaxiv.org/abs/202507.00381", "doi": "10.12074/202507.00381", "keywords": [ "悲伤", "亲社会行为", "三水平元分析", "调节效应", "教育心理学" ], "citations": [ "ChinaXiv:202507.00381", "CSTR:.cn", "https://www.chinaxiv.org/abs/202507.00381v1" ], "sourceId": "ChinaXiv:202507.00381", "chinaXiv": { "canonicalId": "ChinaXiv:202507.00381", "versionId": "ChinaXiv:202507.00381", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=184b9239-7cf9-49b9-8794-581a4fd5085a&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202507.00381v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323530", "title": "网络首发 --> 多通道类别学习的认知特征与神经机制：EEG与DDM证据", "authors": "吴洁, 车子轩", "source": "ChinaXiv", "field": "心理学", "date": "2025-07-04", "abstract": "多通道类别学习的认知特征和神经机制对揭示跨通道知识表征规律具有关键意义。本研究结合事件相关电位技术与漂移扩散模型，系统考察多通道类别学习的认知特征和神经机制。行为结果显示，相较于学习前期，学习中期和后期在行为层面表现出正确率和漂移率显著提升，反应时显著降低，同时决策起始点向正确选项偏移。神经层面发现，学习中期和学习后期引发N1、P1、N250、FSP(Frontal Selection Positivity）及LPC（Late Positive Component)振幅的变化；时频分析显示 Theta、Alpha 及 Delta 频段能量显著衰减。回归分析表明N250-FSP振幅和Theta振荡共同解释漂移率变异，而P1、N250-FSP和LPC可预测决策起始点偏移。研究表明，学习训练通过双重机制优化决策效能：（1）信息积累速率提升与N250-FSP振幅降低及Theta频段能量衰减相关；（2）决策起始点偏移由早期感知编码（P1）、特征辨别（N250-FSP）和记忆提取（LPC）的协同作用驱动。", "url": "https://www.chinaxiv.org/abs/202507.00049", "doi": "10.12074/202507.00049", "keywords": [ "多感官", "类别学习", "漂移扩散模型", "EEG", "认知心理学" ], "citations": [ "ChinaXiv:202507.00049", "CSTR:.cn", "https://www.chinaxiv.org/abs/202507.00049v1" ], "sourceId": "ChinaXiv:202507.00049", "chinaXiv": { "canonicalId": "ChinaXiv:202507.00049", "versionId": "ChinaXiv:202507.00049", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=cf886501-fb17-4a5b-b940-aae0c9dfe7bb&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202507.00049v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323431", "title": "网络首发 --> 关于促进葛洲坝下中华鲟繁殖群体恢复的遗传干预构想", "authors": "杨海乐", "source": "ChinaXiv", "field": "生物学", "date": "2025-06-18", "abstract": "葛洲坝截流后，中华鲟种群陷入螺旋衰退，受后续涉水工程等的进一步影响，中华鲟种群快速衰减，并于2013年首次出现自然繁殖中断。其中的关键在于，中华鲟自然种群未能及时适应葛洲坝截流后的洄游繁殖条件变化。本文从恢复中华鲟野外可持续种群的目标出发，提出促进中华鲟适应葛洲坝截流后洄游繁殖条件的需求，然后从种群遗传的生态学适应角度分析中华鲟繁殖群体适应葛洲坝截流后洄游繁殖条件的可能性，探讨了通过遗传干预促进中华鲟葛洲坝下繁殖群体恢复的可能性，并梳理了通过遗传干预促进中华鲟葛洲坝下繁殖群体恢复的具体困难及未来构想。期待本文能够引起大家对中华鲟种群遗传适应问题的关注和讨论，促进各方在中华鲟保种繁育、增殖放流、种群恢复的细节问题上进一步凝聚共识。", "url": "https://www.chinaxiv.org/abs/202411.00256", "doi": "10.12074/202411.00256", "keywords": [ "中华鲟", "洄游节律", "遗传结构", "等位基因", "基因频率", "遗传管理", "适应", "种群恢复", "生态学" ], "citations": [ "ChinaXiv:202411.00256", "CSTR:.cn", "https://www.chinaxiv.org/abs/202411.00256v2", "https://www.chinaxiv.org/abs/202411.00256v1" ], "sourceId": "ChinaXiv:202411.00256", "chinaXiv": { "canonicalId": "ChinaXiv:202411.00256", "versionId": "ChinaXiv:202411.00256", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=cf1c0f3f-942f-472e-9513-2b687b55d797&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202411.00256v2", "https://www.chinaxiv.org/abs/202411.00256v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323530", "title": "网络首发 --> 非体面工作对其从业者工作意义感的影响机制", "authors": "张光磊, 朱时佳, 王华英, 何宇恒", "source": "ChinaXiv", "field": "管理学", "date": "2025-05-21", "abstract": "非体面工作是指可能会给从业者造成身体、社交或道德层面的污点，令人反感或有损个人尊严的职业或工作任务。非体面工作从业者的工作意义感一直是该领域关注的重要话题。现有研究主要从个体或内群体视角出发，探讨从业者工作组文化或职业意识形态及个人正常化策略对其工作意义建构的影响。然而，关于非体面工作从业者在工作意义建构过程中所体现的共生性维度与他人维度的系统研究仍较匮乏，社会支持在其中的边界作用亦未得到充分揭示。因此，本研究拟从社会支持视角出发，基于工作意义构建四象限理论框架——“能动-共生”和“自我-他人”维度，系统探讨非体面工作从业者工作意义建构的个体与人际机制。预期成果将有助于从更全面的视角理解非体面工作从业者工作意义的构建机制，并在实践中通过管理个体或人际因素，启发员工工作意义的建构。", "url": "https://www.chinaxiv.org/abs/202505.00212", "doi": "10.12074/202505.00212", "keywords": [ "非体面工作", "职业污名", "工作意义感", "“能动-共生”和“自我-他人”理论框架", "社会支持", "人力资源开发与管理" ], "citations": [ "ChinaXiv:202505.00212", "CSTR:.cn", "https://www.chinaxiv.org/abs/202505.00212v1" ], "sourceId": "ChinaXiv:202505.00212", "chinaXiv": { "canonicalId": "ChinaXiv:202505.00212", "versionId": "ChinaXiv:202505.00212", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=23eb4d9f-6226-4803-94dc-90bf1acd53d6&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202505.00212v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323431", "title": "网络首发 --> 所谓影响关系有待商榷：对温忠麟等人（2024）的评论 「open review」", "authors": "葛枭语", "source": "ChinaXiv", "field": "心理学", "date": "2025-03-03", "abstract": "温忠麟等人（2024）在《心理学报》发文聚焦长期以来用法模糊的“影响”一词，并提出“影响关系”概念，或将改变汉语心理学界接下来的语用实践。然而，该文存在若干疑点：“影响”一词无论汉英、无论大众或学界，均视为因果语言，难以被作者说服相信不传达因果意涵；“影响关系”缺失明确定义，似与因果关系并无本质差异；混淆目标与实现目标的手段，由于在手段上无法为因果目标提供因果证据，便创设一个不同于因果和相关关系的第三种目标，是奇怪的。更重要的是，共变且有方向性的变量关系并非如作者所言未被命名，一直被学界称为“预测”。据此，此评论旨在提醒学界同仁考虑描述相关情形的其它可能办法、审慎决策是否将所谓“影响关系”引入研究。", "url": "https://www.chinaxiv.org/abs/202410.00098", "doi": "10.12074/202410.00098", "keywords": [ "影响关系", "相关关系", "因果关系", "影响因素", "预测性研究", "心理学其他学科" ], "citations": [ "ChinaXiv:202410.00098", "CSTR:.cn", "https://www.chinaxiv.org/abs/202410.00098v2", "https://www.chinaxiv.org/abs/202410.00098v1" ], "sourceId": "ChinaXiv:202410.00098", "chinaXiv": { "canonicalId": "ChinaXiv:202410.00098", "versionId": "ChinaXiv:202410.00098", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=daf9c3c1-e67a-45aa-b5a7-20c953d98670&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202410.00098v2", "https://www.chinaxiv.org/abs/202410.00098v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323431", "title": "网络首发 --> Solving the all pairs shortest path problem after minor update of a large dense graph", "authors": "Gangli Liu", "source": "ChinaXiv", "field": "计算机科学", "date": "2025-02-05", "abstract": "The all pairs shortest path problem is a fundamental optimization problem in graph theory. We deal with re-calculating the all-pairs shortest path (APSP) matrix after a minor modification of a weighted dense graph, e.g., adding a node, removing a node, or updating an edge. We assume the APSP matrix for the original graph is already known. The graph can be directed or undirected. A cold-start calculation of the new APSP matrix by traditional algorithms, like the Floyd-Warshall algorithm or Dijkstra’s algorithm, needs $ O(n^3) $ time. We propose two algorithms for warm-start calculation of the new APSP matrix. The best case complexity for a warm-start calculation is $ O(n^2) $, the worst case complexity is $ O(n^3) $. We implemented the algorithms and tested their performance with experiments. The result shows a warm-start calculation can save a great portion of calculation time, compared with cold-start calculation.", "url": "https://www.chinaxiv.org/abs/202412.00242", "doi": "10.12074/202412.00242", "keywords": [ "All pairs shortest path", "Shortest path problem", "计算机科学的集成理论" ], "citations": [ "ChinaXiv:202412.00242", "CSTR:.cn", "https://www.chinaxiv.org/abs/202412.00242v6", "https://www.chinaxiv.org/abs/202412.00242v5", "https://www.chinaxiv.org/abs/202412.00242v4", "https://www.chinaxiv.org/abs/202412.00242v3", "https://www.chinaxiv.org/abs/202412.00242v2", "https://www.chinaxiv.org/abs/202412.00242v1" ], "sourceId": "ChinaXiv:202412.00242", "chinaXiv": { "canonicalId": "ChinaXiv:202412.00242", "versionId": "ChinaXiv:202412.00242", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=77c7eab5-55ae-404e-b6a2-3780d0b7bf8e&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202412.00242v6", "https://www.chinaxiv.org/abs/202412.00242v5", "https://www.chinaxiv.org/abs/202412.00242v4", "https://www.chinaxiv.org/abs/202412.00242v3", "https://www.chinaxiv.org/abs/202412.00242v2", "https://www.chinaxiv.org/abs/202412.00242v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323431", "title": "网络首发 --> 空间导航能力性别差异的三水平元分析", "authors": "薛笑然, 崔伟, 张丽", "source": "ChinaXiv", "field": "心理学", "date": "2024-12-26", "abstract": "空间导航是不可或缺的基本认知能力，尽管已有大量研究探讨其性别差异，但关于差异的存在和大小尚无定论。本研究对173项研究(总样本量N=26604)和372个独立效应量进行三水平元分析，结果表明，大多数条件下男性的空间导航能力强于女性，但性别差异受年龄、表征方式、时间限制、任务环境、测试场景、辅+助装备的调节，在婴幼儿期、成年晚期的人群中，以及室内–室外双重测试和无辅助设备条件下，空间导航能力的性别差异不显著。本研究明确了空间导航能力的性别差异及其调节因素，为教育实践中缩小性别差异提供了参考。", "url": "https://www.chinaxiv.org/abs/202412.00341", "doi": "10.12074/202412.00341", "keywords": [ "空间导航能力", "性别差异", "三水平元分析", "调节效应", "认知心理学" ], "citations": [ "ChinaXiv:202412.00341", "CSTR:.cn", "https://www.chinaxiv.org/abs/202412.00341v1" ], "sourceId": "ChinaXiv:202412.00341", "chinaXiv": { "canonicalId": "ChinaXiv:202412.00341", "versionId": "ChinaXiv:202412.00341", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=4eda7b79-6c8f-4557-bc9a-281c6b5569bd&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202412.00341v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323431", "title": "网络首发 --> 流动性视角下地方污名的形成机制", "authors": "黎耀奇, 曾馨莹", "source": "ChinaXiv", "field": "心理学", "date": "2024-12-08", "abstract": "地方被污名化的现象层出不穷，严重损害了地方形象以及相关群体的福祉，阻碍了社会平等、和谐与稳定。已有研究多采用故事性叙事去解释地方污名，但对于为何以及如何形成地方污名尚不明晰。本研究拟基于流动性视角，以地方刻板印象为核心，提出地方污名形成机制的研究构想。具体地，本研究先依据地方性冲突事件将地方污名划分为道德、治安和环境三种类型，并在此基础上通过揭示要素流动在地方污名形成过程中的潜在影响，建构地方性冲突事件对地方污名的作用机制与边界条件。预期研究有助于加强对地方污名的理解，补充已有研究在地方污名形成机制上的研究缺口，并为缓解地方污名泛化的现实问题提供参考与借鉴。", "url": "https://www.chinaxiv.org/abs/202412.00084", "doi": "10.12074/202412.00084", "keywords": [ "地方污名", "负面刻板印象", "流动性", "故事性叙事", "社会心理学" ], "citations": [ "ChinaXiv:202412.00084", "CSTR:.cn", "https://www.chinaxiv.org/abs/202412.00084v1" ], "sourceId": "ChinaXiv:202412.00084", "chinaXiv": { "canonicalId": "ChinaXiv:202412.00084", "versionId": "ChinaXiv:202412.00084", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=f8fae166-6687-48f9-ab39-5d468f82d1cb&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202412.00084v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323431", "title": "网络首发 --> 基于欧氏度规的四维速度矢量及其应用", "authors": "刘小灵", "source": "ChinaXiv", "field": "物理学", "date": "2024-11-20", "abstract": "基于闵氏时空定义的四维速度矢量，并非由运动物体在四个维度各自的运动速度构成，缺乏直观的物理意义，提升了计算和分析的复杂度。本文提出了一种基于欧氏度规，四个分量与物体在四维时空的运动速度一一对应的四维速度矢量定义，并建立了与此四维速度矢量匹配的时空坐标系及其线元计算方法。本文基于此四维速度矢量和坐标系对狭义相对论和广义相对论中的若干问题进行了演算，得出了闵氏时空无法适用欧氏度规的原因。特别是从欧氏四维速度变化带来的动量和能量变化的角度，揭示了引力是时空结构而不是力的物理原理，说明了欧氏度规在相对论计算中比闵氏度规具有更显著的直观性。", "url": "https://www.chinaxiv.org/abs/202411.00029", "doi": "10.12074/202411.00029", "keywords": [ "四维速度矢量", "闵氏时空度规", "欧氏时空度规", "普通物理:统计和量子力学,量子信息等" ], "citations": [ "ChinaXiv:202411.00029", "CSTR:.cn", "https://www.chinaxiv.org/abs/202411.00029v2", "https://www.chinaxiv.org/abs/202411.00029v1" ], "sourceId": "ChinaXiv:202411.00029", "chinaXiv": { "canonicalId": "ChinaXiv:202411.00029", "versionId": "ChinaXiv:202411.00029", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=8a257bda-6266-41b7-839f-295eb61a9f0c&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202411.00029v2", "https://www.chinaxiv.org/abs/202411.00029v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323430", "title": "网络首发 --> 视觉注意对决策的影响及其作用机制", "authors": "张湘一, 吴一琳", "source": "ChinaXiv", "field": "心理学", "date": "2024-07-31", "abstract": "视觉注意作为一种信息选择和认知资源分配机制，不仅是信息加工和认知功能的基础，也是完成各种社会行为的重要条件。大量研究证实视觉注意影响了个体的决策偏好。本文在全面回顾以往研究的基础上，从知觉决策、偏好决策和其他社会决策三个方面梳理了视觉注意对决策的影响；并且，总结了简单暴露效应(mere exposure effect)、注视层叠假说(gaze cascade hypothesis)、序列抽样模型(sequential sampling model)和自适应注意表征模型(adaptive attention representation model)对视觉注意影响三种决策作用机制的解释。未来研究可以考虑设置具有不同偏好程度的选项、决策情境或视觉环境的调节因素、其他类型的注意在决策中的作用以深化关于视觉注意对决策的影响及其作用机制问题的理解。", "url": "https://www.chinaxiv.org/abs/202408.00005", "doi": "10.12074/202408.00005", "keywords": [ "视觉注意", "知觉决策", "偏好决策", "社会决策", "漂移扩散模型", "认知心理学" ], "citations": [ "ChinaXiv:202408.00005", "CSTR:.cn", "https://www.chinaxiv.org/abs/202408.00005v1" ], "sourceId": "ChinaXiv:202408.00005", "chinaXiv": { "canonicalId": "ChinaXiv:202408.00005", "versionId": "ChinaXiv:202408.00005", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=1d5f277f-d373-454d-a0ef-166f12f8e7f2&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202408.00005v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323430", "title": "网络首发 --> 选我所看，看我所选？消费决策中注意力漂移扩散模型的应用与争论", "authors": "杨依琳, 刘梦颖, 林欣, 黄建平", "source": "ChinaXiv", "field": "心理学", "date": "2024-07-05", "abstract": "注意力与价值之间的因果关系是决策领域的一个核心议题。借助于计算建模的发展，特别是注意力漂移扩散模型 (attentional drift diffusion model, aDDM)的应用，研究者发现注意力可以放大选项价值以引导决策，即“选我所看”。但该模型在实际应用中的局限和矛盾结果使得其所支持的观点备受质疑，反而暗示了一种相反的因果关系——“看我所选”，即消费者基于商品价值做出选择，注意力仅被动反映价值。本综述旨在通过探讨aDDM的应用价值及其在揭示注意力与价值关系方面的矛盾结果，以期阐明两者之间的因果关系。结果发现，尽管aDDM为 “选我所看”提供了切实证据，但其证据力度并不足以完全支持该观点。而且，建模结果揭示了注意力与价值之间存在更为复杂的相互作用，暗示两者之间可能表现一种互为因果的动态关系。未来研究需细化注意力的时间窗口，并在更加开放的理论框架下探讨这一因果关系，同时关注其对消费决策领域的应用价值。", "url": "https://www.chinaxiv.org/abs/202407.00098", "doi": "10.12074/202407.00098V1", "keywords": [ "注意", "消费者决策", "注意力漂移扩散模型", "因果关系", "价值计算", "应用心理学" ], "citations": [ "ChinaXiv:202407.00098", "CSTR:.cn", "https://www.chinaxiv.org/abs/202407.00098v1" ], "sourceId": "ChinaXiv:202407.00098", "chinaXiv": { "canonicalId": "ChinaXiv:202407.00098", "versionId": "ChinaXiv:202407.00098", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=4e435561-9f09-404b-930c-bfc9da8d2148&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202407.00098v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323430", "title": "网络首发 --> 简体中文LIWC2024(SCLIWC2024)词典的修订与验证", "authors": "崔雪婷, 陈思仪, 赵楠, 刘晓倩, 朱廷劭", "source": "ChinaXiv", "field": "心理学", "date": "2024-04-09", "abstract": "近年来，字词分析取向的方法逐渐受到重视，特别是语言探索与字词计数(Linguistic Inquiry and Word Count, LIWC)工具，它的问世让许多心理学家对语言分析研究重新燃起热情。最新版本LIWC-22词典的修订新增了许多心理变量，在增加了LIWC工具的应用潜力的同时也使其更加完善。为进一步推动LIWC工具中文化的进程，我们对多个版本的中文LIWC词典进行汇总，修订形成了SCLIWC2024，并对其效度进行了检验。研究一中，我们对照LIWC-22词典和CLIWC2015词典，以SCLIWC词典为基础，修订形成了SCLIWC2024词典。研究二中，我们进行了两项实验来检测SCLIWC2024在不同类型网络文本心理表达的有效性，并回答了如何更有效地使用SCLIWC2024来检测社交网络平台短文本的心理表达的重要问题。", "url": "https://www.chinaxiv.org/abs/202404.00159", "doi": "10.12074/202404.00159V1", "keywords": [ "LIWC", "词典构建", "SCLIWC2024", "效度检验", "网络文本分析", "应用心理学" ], "citations": [ "ChinaXiv:202404.00159", "CSTR:.cn", "https://www.chinaxiv.org/abs/202404.00159v1" ], "sourceId": "ChinaXiv:202404.00159", "chinaXiv": { "canonicalId": "ChinaXiv:202404.00159", "versionId": "ChinaXiv:202404.00159", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=710cf4d8-bab0-45c5-9613-0a582064ac5d&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202404.00159v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323331", "title": "网络首发 --> 密集追踪研究中测验信度的估计：多层结构和动态特性的视角", "authors": "罗晓慧, 刘红云", "source": "ChinaXiv", "field": "心理学", "date": "2023-11-28", "abstract": "随着密集追踪研究在心理学等社会科学领域的广泛运用，密集追踪情境中测验信度的估计也受到越来越多研究者的关注。早期沿用横断研究中信度估计思想或基于概化理论的信度估计方法存在诸多局限，并不适用于密集追踪的情境。针对密集追踪数据的多层结构和动态特性这两大特点，可基于多层验证性因子分析、动态因子分析和动态结构方程模型估计密集追踪研究中测验的信度。通过实证数据的演示与比较，讨论三种估计方法的特点和适用情境。未来研究可基于其它密集追踪模型探讨测验信度的估计，也应重视测验信度的检验与报告。", "url": "https://www.chinaxiv.org/abs/202312.00008", "doi": "10.12074/202312.00008V1", "keywords": [ "密集追踪研究", "信度", "多层结构", "动态特性", "动态结构方程模型", "心理测量" ], "citations": [ "ChinaXiv:202312.00008", "CSTR:.cn", "https://www.chinaxiv.org/abs/202312.00008v1" ], "sourceId": "ChinaXiv:202312.00008", "chinaXiv": { "canonicalId": "ChinaXiv:202312.00008", "versionId": "ChinaXiv:202312.00008", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=b075885e-0c8d-4c7f-af8d-4c3274942a59&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202312.00008v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323331", "title": "网络首发 --> 任务相关性对数量感序列依赖效应的影响", "authors": "刘雨杰, 刘晨淼, 周丽琴, 周可", "source": "ChinaXiv", "field": "心理学", "date": "2023-11-20", "abstract": "序列依赖效应反映了当前的知觉体验不仅取决于当下的刺激输入，还受到近期历史的影响。这一效应对于我们在动态变化的环境中形成相对稳定的知觉至关重要。本研究使用点阵作为刺激材料，在数量/面积(实验一)或数量/大小(实验二)两个维度上进行正交设计，旨在通过估计任务探索任务相关性如何影响线性分布特征的序列依赖效应。结果显示无论特征是否与任务相关，前一试次与当前试次同一特征总会对当前试次的知觉产生相反的影响。对于任务相关特征，前一试次产生的序列依赖始终为排斥效应。而对于任务无关特征，如果在当前试次中无关特征对被试的知觉反应有正向预测作用，则前一试次无关特征产生排斥的序列依赖效应；反之，如果在当前试次中无关特征对被试的知觉反应有负向预测，则前一试次无关特征产生吸引的序列依赖效应。任务相关性对序列依赖效应的影响主要体现在效应幅值的降低。这些发现揭示了线性分布特征的序列依赖效应受任务相关性以及特征本身特性的共同影响，而无关特征的序列依赖效应则暗示在客体水平也可以产生序列依赖效应。", "url": "https://www.chinaxiv.org/abs/202311.00248", "doi": "10.12074/202311.00248V1", "keywords": [ "序列依赖效应", "数量感", "任务相关性", "线性分布的特征", "认知心理学" ], "citations": [ "ChinaXiv:202311.00248", "CSTR:.cn", "https://www.chinaxiv.org/abs/202311.00248v1" ], "sourceId": "ChinaXiv:202311.00248", "chinaXiv": { "canonicalId": "ChinaXiv:202311.00248", "versionId": "ChinaXiv:202311.00248", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=ce3b0157-540b-443b-b9fd-4de5b1018238&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202311.00248v1" ] }, "sources": [ "ChinaXiv" ] }, { "id": "chinaxiv-6368696e617869763a3230323331", "title": "网络首发 --> 基于信号检测论的认知诊断评估：构建与应用", "authors": "郭磊, 秦海江", "source": "ChinaXiv", "field": "心理学", "date": "2023-11-13", "abstract": "作答选择题可被看作从噪音中提取信号的过程，研究提出了一种基于信号检测论的认知诊断模型(SDT-CDM)。新模型的优势在于：(1)无需对选项进行属性层面的编码。(2)能获得传统诊断模型无法提供的题目区分度和难度参数。(3)可以直接表达每个选项之间的合理性差异，对题目性能刻画更加细微全面。两个模拟研究结果表明：(1)EM算法可以实现对新模型的参数估计过程，便捷有效。(2)SDT-CDM具备良好性能，分类准确性和参数估计精度较高以外，还能提供选项层面的估计信息，用于题目质量诊断与修订。(3)属性数量、题目质量与样本量等因素会影响SDT-CDM的表现。(4)与称名诊断模型NRDM相比，SDT-CDM在所有实验条件下对被试的分类准确性更高。实证研究表明：SDT-CDM比NRDM具有更好的模型数据拟合结果，其分类准确性和一致性更高，尤其当属性考察次数较少时具有很强的稳定性，难度和区分度参数与IRT模型估计结果的相关性也更高，值得推广。", "url": "https://www.chinaxiv.org/abs/202311.00128", "doi": "10.12074/202311.00128V1", "keywords": [ "信号检测论", "认知诊断", "选择题", "EM算法", "心理测量" ], "citations": [ "ChinaXiv:202311.00128", "CSTR:.cn", "https://www.chinaxiv.org/abs/202311.00128v1" ], "sourceId": "ChinaXiv:202311.00128", "chinaXiv": { "canonicalId": "ChinaXiv:202311.00128", "versionId": "ChinaXiv:202311.00128", "pdfUrl": "https://www.chinaxiv.org/user/download.htm?uuid=6033d90a02c54178b83092659631ed58&filetype=pdf", "cstr": ".cn", "versionLinks": [ "https://www.chinaxiv.org/abs/202311.00128v1" ] }, "sources": [ 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